Khanavi Mahnaz, Vatandoost Hassan, Khosravi Dehaghi Nafiseh, Sanei Dehkordi Alireza, Sedaghat Mohammad Mehdi, Hadjiakhoondi Abbas, Hadjiakhoondi Farzaneh
Department of Pharmacognosy and Traditional Iranian Medicine Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Acta Med Iran. 2013 Apr 6;51(3):141-7.
Malaria is considered a major health problem in Iran. There are different methods for vector control. In this study we tested the larvicidal effects of some Iranian plants. The methanolic extracts of 11 plants were prepared with percolation method. The larvicidal activities of them against malaria vector, Anopheles stephensi were studied using World Health Organization standard method. All LC50 values of methanolic extracts of plants that we screened were lower than 300 ppm. The methanolic extract of aerial parts of Lawsonia inermis and Stachys byzantina showed high larvicidal activity with LC50 values 69.40 ppm and 103.28 ppm respectively. The results obtained from this study suggest that the methanolic extracts of these plants have larvicidal effects against Anopheles stephensi larvae and could be useful in the search for new natural larvicidal compounds.
疟疾在伊朗被视为一个主要的健康问题。有不同的病媒控制方法。在本研究中,我们测试了一些伊朗植物的杀幼虫效果。采用渗漉法制备了11种植物的甲醇提取物。使用世界卫生组织标准方法研究了它们对疟疾媒介斯氏按蚊的杀幼虫活性。我们筛选的植物甲醇提取物的所有LC50值均低于300 ppm。无刺指甲花地上部分和拜占庭水苏的甲醇提取物表现出高杀幼虫活性,LC50值分别为69.40 ppm和103.28 ppm。本研究获得的结果表明,这些植物的甲醇提取物对斯氏按蚊幼虫具有杀幼虫作用,可能有助于寻找新的天然杀幼虫化合物。