Manganaro Lucia, Bernardo Silvia, Sergi Maria Eleonora, Sollazzo Paolo, Vinci Valeria, De Grazia Alessandra, Clerico Anna, Mollace Maria Giovanna, Saldari Matteo
Department of Radiological Oncological and Anatomopathological Sciences, Umberto I Hospital, "La Sapienza" University of Rome, Viale Regina Elena 324, 00161 Rome, Italy.
Case Rep Radiol. 2013;2013:940160. doi: 10.1155/2013/940160. Epub 2013 Mar 30.
Burkitt's lymphoma is a rare non-Hodgkin's lymphoma which can occasionally involve the ovary and may cause confusion for the clinician since its presentation might mimic other much more frequent tumors. We present a case of a 23-year-old woman with sporadic Burkitt's lymphoma presented as advanced ovarian cancer with bilateral ovarian masses, peritoneal carcinomatosis, ascites, and marked elevation of CA-125. Liver involvement and atypical bone lesions, such as the cranial vault and the iliac wing, were also detected without evidence of lymphadenopathy. We describe the MRI and CT findings of simultaneous ovarian and bone lesions, which have never been reported in literature in a patient with Burkitt's lymphoma, before and after one cycle of chemotherapy. In evaluating any ovarian neoplasm in a young woman, Burkitt's lymphoma should be considered as a possibility, particularly if associated with bone lesions. MRI is the most useful tool to characterize the ovarian lesions and suggest the diagnosis before the histopathological results.
伯基特淋巴瘤是一种罕见的非霍奇金淋巴瘤,偶尔可累及卵巢,因其表现可能类似其他更常见的肿瘤,这可能会给临床医生带来困惑。我们报告一例23岁女性散发性伯基特淋巴瘤,表现为晚期卵巢癌,伴有双侧卵巢肿块、腹膜癌转移、腹水及CA-125显著升高。还检测到肝脏受累以及颅骨穹窿和髂骨翼等非典型骨病变,且无淋巴结病证据。我们描述了该患者在化疗一个周期前后同时出现的卵巢和骨病变的MRI及CT表现,此前文献中从未报道过伯基特淋巴瘤患者出现这种情况。在评估年轻女性的任何卵巢肿瘤时,应考虑伯基特淋巴瘤的可能性,尤其是伴有骨病变时。MRI是在组织病理学结果出来之前,用于描述卵巢病变特征并提示诊断的最有用工具。