Ismail Sawsan, Abdulrahman Seif-Aldin, Muhammad Ibrahim, Ghanem Abdulmoniem, Daoud Ali, Alshehabi Zuheir
Department of Pathology, Faculty of Medicine, Cancer Research Center, Tishreen University, Lattakia, Syria.
Faculty of Medicine, Cancer Research Center, Tishreen University, Lattakia, Syria.
Ann Med Surg (Lond). 2022 Mar 3;75:103453. doi: 10.1016/j.amsu.2022.103453. eCollection 2022 Mar.
Burkitt's lymphoma is an aggressive type of non-Hodgkin lymphoma that represents approximately 30% of pediatric lymphomas and less than 5% of all pediatric malignancies. Although the involvement of the gastrointestinal tract is a common finding in sporadic Burkitt's lymphoma, primary intestinal lymphomas still represent a rare entity.
We are reporting the case of an 11-year-old Syrian male who presented to our hospital with complaints of abdominal pain, distention, and tenderness. Clinical and radiologic examinations demonstrated moderate ascites with an abdominal mass. Interestingly, the cytological study of the ascites revealed the diagnosis of Burkitt's lymphoma which was later confirmed by histopathological and immunohistochemical examinations.
Pleural effusions are a common finding in extranodal lymphomas, whereas ascites is considered a rare initial presentation constituting less than 2% of lymphoma cases.
We aimed to present an extremely rare case of a primary intestinal Burkitt's lymphoma initially presenting with ascites, highlighting the major role of the cytological study of ascites in the primary diagnosis, and the essential role of histological and immunohistochemical examinations in confirming the diagnosis in challenging cases.
伯基特淋巴瘤是一种侵袭性非霍奇金淋巴瘤，约占儿童淋巴瘤的30%，在所有儿童恶性肿瘤中占比不到5%。尽管胃肠道受累在散发性伯基特淋巴瘤中很常见，但原发性肠道淋巴瘤仍然是一种罕见的疾病。
我们报告了一名11岁叙利亚男性的病例，他因腹痛、腹胀和压痛前来我院就诊。临床和影像学检查显示中度腹水并伴有腹部肿块。有趣的是，腹水的细胞学研究确诊为伯基特淋巴瘤，随后经组织病理学和免疫组织化学检查得以证实。
胸腔积液在结外淋巴瘤中很常见，而腹水被认为是一种罕见的首发表现，在淋巴瘤病例中占比不到2%。
我们旨在呈现一例极为罕见的原发性肠道伯基特淋巴瘤，最初表现为腹水，强调腹水细胞学研究在初步诊断中的主要作用，以及组织学和免疫组织化学检查在疑难病例确诊中的关键作用。
