• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

携带有 BRCA1 和 BRCA2 基因突变生活:学习如何适应一种虚拟的慢性疾病。

Living with the BRCA1 and BRCA2 genetic mutation: learning how to adapt to a virtual chronic illness.

机构信息

a Faculty of Education , University of Ottawa , Ottawa , Canada .

出版信息

Psychol Health Med. 2014;19(1):103-14. doi: 10.1080/13548506.2013.779729. Epub 2013 Apr 23.

DOI:10.1080/13548506.2013.779729
PMID:23607692
Abstract

The objective of this study was to understand how women living with the BRCA1 and BRCA2 genetic mutation adapt to this life transition and to identify the main adaptive tasks. A qualitative inquiry inspired by grounded theory revealed that participants cognitively appraised their test result in the same manner as women who have been diagnosed with breast cancer. Consequently, participants had to adapt to a condition that they perceived as a chronic illness. The following three main tasks were identified: Physical Task: Attempting to Limit the Impact of the Test Result, Psychological Task: Living with Uncertainty, and Social Task: Finding Effective Support. In conclusion, although these women live with the possibility of developing breast cancer, their experiences mirror those of individuals living with a chronic illness, and they must therefore adapt accordingly in a physical, psychological, and social manner.

摘要

本研究旨在了解携带有 BRCA1 和 BRCA2 基因突变的女性如何适应这种生活转变,并确定主要的适应任务。一项受扎根理论启发的定性研究表明,参与者在认知上评估其测试结果的方式与被诊断患有乳腺癌的女性相同。因此,参与者必须适应一种他们认为是慢性病的情况。确定了以下三个主要任务:身体任务:试图限制测试结果的影响,心理任务:生活在不确定性中,社会任务:寻找有效的支持。总之,尽管这些女性有可能患上乳腺癌,但她们的经历与患有慢性病的个体相似,因此她们必须在身体、心理和社会方面相应地进行适应。

相似文献

1
Living with the BRCA1 and BRCA2 genetic mutation: learning how to adapt to a virtual chronic illness.携带有 BRCA1 和 BRCA2 基因突变生活:学习如何适应一种虚拟的慢性疾病。
Psychol Health Med. 2014;19(1):103-14. doi: 10.1080/13548506.2013.779729. Epub 2013 Apr 23.
2
Living with the BRCA genetic mutation: an uncertain conclusion to an unending process.携带有 BRCA 基因突变:一个不确定的结论,一个无尽的过程。
Psychol Health Med. 2013;18(2):125-34. doi: 10.1080/13548506.2012.687827. Epub 2012 Jun 6.
3
Theory development from studies with young women with breast cancer who are BRCA mutation negative.对BRCA基因无突变的年轻乳腺癌女性患者的研究得出的理论
ANS Adv Nurs Sci. 2013 Apr-Jun;36(2):E41-53. doi: 10.1097/ANS.0b013e3182901ff1.
4
'Going-to-have-cancerness': a study of living with increased risk of BRCA1 and BRCA2 mutations for six South Island women.“患癌风险增加症”:对六位南岛女性携带BRCA1和BRCA2基因突变增加风险的生活状况研究
J Prim Health Care. 2010 Dec 1;2(4):311-7.
5
Accommodating risk: responses to BRCA1/2 genetic testing of women who have had cancer.应对风险:癌症女性对BRCA1/2基因检测的反应
Soc Sci Med. 2004 Aug;59(3):553-65. doi: 10.1016/j.socscimed.2003.11.025.
6
[Cognitive, emotional and behavioral impact of an uncertain outcome after study of BRCA1/2: review of the literature].[BRCA1/2基因检测后不确定结果对认知、情绪和行为的影响:文献综述]
Bull Cancer. 2011 Feb;98(2):184-98. doi: 10.1684/bdc.2011.1309.
7
The twilight zone between health and sickness: a qualitative exploration with asymptomatic BRCA1 and 2 mutation carriers.健康与疾病之间的模糊地带:对无症状 BRCA1 和 2 基因突变携带者的定性探索。
Women Health. 2009 Jun;49(4):263-79. doi: 10.1080/03630240903158321.
8
Comparison of individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing with regard to coping, illness perceptions, illness experiences, family system characteristics and hereditary cancer distress.选择进行BRCA1/2或遗传性非息肉病性结直肠癌(HNPCC)基因易感性检测的个体在应对方式、疾病认知、疾病经历、家庭系统特征和遗传性癌症困扰方面的比较。
Patient Educ Couns. 2007 Jan;65(1):58-68. doi: 10.1016/j.pec.2006.05.006. Epub 2006 Jul 26.
9
Clinical characteristics affect the impact of an uninformative DNA test result: the course of worry and distress experienced by women who apply for genetic testing for breast cancer.临床特征会影响无信息价值的DNA检测结果的影响:申请乳腺癌基因检测的女性所经历的担忧和痛苦过程。
J Clin Oncol. 2006 Aug 1;24(22):3672-7. doi: 10.1200/JCO.2005.03.7259.
10
Moving In and Out of the What-Ifs: The Experiences of Unaffected Women Living in Families Where a Breast Cancer 1 or 2 Genetic Mutation Was Not Found.在假设情境中进进出出:未检测出乳腺癌1或2基因突变的家庭中未患病女性的经历
Cancer Nurs. 2017 Sep/Oct;40(5):386-393. doi: 10.1097/NCC.0000000000000438.

引用本文的文献

1
Quality of Life in Adult Individuals Living With or at Risk of a Hereditary Cancer Predisposition Syndrome: A Scoping Review of the Qualitative Literature.患有遗传性癌症易感性综合征或有患该综合征风险的成年个体的生活质量:定性文献的范围综述
Cancer Med. 2025 Sep;14(18):e71069. doi: 10.1002/cam4.71069.
2
Beyond BRCA: A scoping review of person-centred care for women diagnosed with a BRCA gene mutation.超越BRCA:对诊断为BRCA基因突变的女性以患者为中心的护理的范围综述
BMJ Open. 2025 Mar 6;15(3):e094416. doi: 10.1136/bmjopen-2024-094416.
3
Resilience resources and coping strategies of COVID-19 female long haulers: A qualitative study.
COVID-19 女性长期患者的韧性资源和应对策略:一项定性研究。
Front Public Health. 2022 Nov 4;10:970378. doi: 10.3389/fpubh.2022.970378. eCollection 2022.
4
"You Always Have It in the Back of Your Mind"-Feelings, Coping, and Support Needs of Women with Pathogenic Variants in Moderate-Risk Genes for Hereditary Breast Cancer Attending Genetic Counseling in Germany: A Qualitative Interview Study.“你总会记挂在心头”——德国接受遗传咨询的中危遗传性乳腺癌基因致病性变异携带者女性的感受、应对方式和支持需求:一项定性访谈研究。
Int J Environ Res Public Health. 2022 Mar 16;19(6):3525. doi: 10.3390/ijerph19063525.
5
Effect of Inquiry-Based Stress Reduction on Well-being and Views on Risk-Reducing Surgery Among Women With BRCA Variants in Israel: A Randomized Clinical Trial.以色列携带 BRCA 变异的女性中基于探究的减压对幸福感和降低风险手术看法的影响:一项随机临床试验。
JAMA Netw Open. 2021 Dec 1;4(12):e2139670. doi: 10.1001/jamanetworkopen.2021.39670.
6
A Systematic Review of the Psychological Implications of Genetic Testing: A Comparative Analysis Among Cardiovascular, Neurodegenerative and Cancer Diseases.基因检测心理影响的系统评价:心血管疾病、神经退行性疾病和癌症之间的比较分析
Front Genet. 2018 Dec 10;9:624. doi: 10.3389/fgene.2018.00624. eCollection 2018.
7
Perspectives of Women Considering Bilateral Prophylactic Mastectomy and their Peers towards a Telephone-Based Peer Support Intervention.考虑双侧预防性乳房切除术的女性及其同伴对基于电话的同伴支持干预的看法。
J Genet Couns. 2018 Feb;27(1):274-288. doi: 10.1007/s10897-017-0148-x. Epub 2017 Sep 15.
8
Decision making for breast cancer prevention among women at elevated risk.乳腺癌高危女性的预防决策
Breast Cancer Res. 2017 Mar 24;19(1):34. doi: 10.1186/s13058-017-0826-5.