Ulstrup Thomas, Pedersen Finn Møller
Afdeling for Medicinske Mavetarmsygdomme, Odense Universitetshospital, Denmark.
Ugeskr Laeger. 2013 Feb 25;175(9):579-82.
Cholangiocarcinomas (CC) account for approximately 3% of all gastrointestinal cancers with an incidence of about three per 100,000. 70% of CC are perihilar lesions and can be classified according to the Bismuth-Corlette system. At the time of dia-gnosis less than 30% are candidates for complete resection. For nonresectable CC median survival is 4-6 months. Since biliary obstruction is the most common cause of death, biliary stenting has been the standard palliative therapy. Several studies have confirmed that administering photodynamic therapy to perihilar CC improves quality of life and increases median survival time.
胆管癌(CC)约占所有胃肠道癌症的3%,发病率约为十万分之三。70%的胆管癌为肝门周围病变,可根据Bismuth-Corlette系统进行分类。在诊断时,不到30%的患者适合进行根治性切除。对于不可切除的胆管癌,中位生存期为4至6个月。由于胆管梗阻是最常见的死亡原因,胆管支架置入术一直是标准的姑息治疗方法。多项研究证实,对肝门周围胆管癌进行光动力治疗可改善生活质量并延长中位生存时间。