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[一名80岁男性胆管癌的光动力疗法]

[Photodynamic therapy of a cholangiocarcinoma in an 80-year-old man].

作者信息

Ulstrup Thomas, Pedersen Finn Møller

机构信息

Afdeling for Medicinske Mave-tarm-sygdomme, Odense Universitetshospital, Denmark.

出版信息

Ugeskr Laeger. 2013 Feb 25;175(9):583-4.

Abstract

70% of cholangiocarcinomas (CC) are perihilar lesions. At the time of diagnosis few are candidates for complete resection, and the standard palliative therapy has been biliary stenting. Studies have shown that photodynamic therapy (PDT) improves survival time. In this case report we describe an 80-year-old man with rheumatoid arthritis and perihilar CC classified as Bismuth-Corlette type II who successfully underwent PDT as the first patient in Denmark. The treatment was well tolerated with no phototoxic skin reaction, and a subsequent endoscopic retrograde cholangiopancreatography showed reduction of tumour.

摘要

70%的胆管癌(CC)为肝门部病变。在诊断时,很少有患者适合进行根治性切除,标准的姑息治疗方法一直是胆管支架置入术。研究表明,光动力疗法(PDT)可延长生存时间。在本病例报告中,我们描述了一名80岁患类风湿性关节炎的男性,其肝门部CC被分类为Bismuth-Corlette II型,作为丹麦首例患者成功接受了PDT治疗。该治疗耐受性良好,未出现光毒性皮肤反应,随后的内镜逆行胰胆管造影显示肿瘤缩小。

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