[二氯甲烷 - 水介质体系中竹桃霉素提取的研究]
[Study of oleandomycin extraction in a methylene chloride-aqueous medium system].
作者信息
Slavin A A, Orlievskaia O V, Velichko L S, Reshetov V A, Komarov E V, Fradkova T A
出版信息
Antibiot Khimioter. 1990 Mar;35(3):15-7.
PMID:2360849
Abstract
Influence of pH, temperature and oleandomycin concentration on distribution of the antibiotic in the methylene chloride-aqueous medium system was studied. It was shown that the oleandomycin distribution coefficient did not depend on the antibiotic concentration within the ranges of 2000 to 20,000 micrograms/ml. An equation defining relationship between the oleandomycin distribution coefficient and pH of the aqueous phase is presented.
摘要
研究了pH值、温度和竹桃霉素浓度对该抗生素在二氯甲烷-水介质体系中分布的影响。结果表明，在2000至20000微克/毫升的范围内，竹桃霉素的分配系数与抗生素浓度无关。给出了一个定义竹桃霉素分配系数与水相pH值之间关系的方程。
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