Pradas J, Illa I
Unidad de Neuromuscular, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona.
Neurologia. 1990 Jan;5(1):11-3.
The influence of age at onset, sex, duration of disease and severity degree on the response to therapy have been evaluated in 30 patients with myasthenia gravis treated with prednisone. During the evaluation period (3 months as a maximum) the patients were only treated with prednisone. The evaluation of the response was based on the use of quantified tests of clinical fatigability. Among all the evaluated factors, only the age at onset seemed to have a predictive value of the response to prednisone therapy. The patients older than 40 years and particularly those older than 60 years showed a better response than younger patients.
对30例接受泼尼松治疗的重症肌无力患者，评估了发病年龄、性别、病程和严重程度对治疗反应的影响。在评估期（最长3个月）内，患者仅接受泼尼松治疗。治疗反应的评估基于临床疲劳量化测试。在所有评估因素中，只有发病年龄似乎对泼尼松治疗反应具有预测价值。40岁以上的患者，尤其是60岁以上的患者，比年轻患者显示出更好的治疗反应。
