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[成人病毒性或可能为病毒性病因的脑膜炎:325例研究]

[Meningitis of viral or possible viral etiology in adults: study of 325 cases].

作者信息

Martínez-Martín P, Herreros A, Téllez A, Echevarría J M

机构信息

Servicio de Neurología, Hospital del Rey, Majadahonda, Madrid.

出版信息

Neurologia. 1990 Jan;5(1):4-10.

PMID:2361032
Abstract

During five consecutive years, 325 patients older than 14 years with acute possibly viral acute meningitis (VAM) were evaluated. Demographical, clinical and laboratory data were obtained. In 50.5% of cases the etiological investigation of the disease was undertaken with different methods. From the diagnostic point of view, the findings can be nonspecific or equivocal, and only the judicious assessment of clinical, laboratory (blood CRP) and the overall CSF measurements can prevent errors in an early phase. The viral studies demonstrated a specific etiology in 46% of the instances where they were carried out. The viruses accounting for VAM which were more commonly identified included varicella-zoster, enteroviruses, parotiditis and herpes simplex.

摘要

在连续五年中,对325名14岁以上患有急性可能病毒性急性脑膜炎(VAM)的患者进行了评估。获取了人口统计学、临床和实验室数据。在50.5%的病例中,采用不同方法对疾病进行了病因学调查。从诊断角度来看,检查结果可能是非特异性的或模棱两可的,只有对临床、实验室(血液CRP)和脑脊液综合测量结果进行审慎评估,才能在早期阶段避免错误。病毒学研究在46%进行检测的病例中发现了特定病因。导致VAM的更常见病毒包括水痘-带状疱疹病毒、肠道病毒、腮腺炎病毒和单纯疱疹病毒。

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Quantitative real time PCR detection of Varicella-zoster virus DNA in cerebrospinal fluid in patients with neurological disease.定量实时PCR检测神经系统疾病患者脑脊液中的水痘-带状疱疹病毒DNA
Med Microbiol Immunol. 2005 Jan;194(1-2):7-12. doi: 10.1007/s00430-003-0202-1. Epub 2004 Mar 2.