社区中的骨质疏松症：自我报告的诊断人群的敏感度估计和药物使用情况。
Osteoporosis in the community: Sensitivity of self-reported estimates and medication use of those diagnosed with the condition.
机构信息
The University of Adelaide, Population Research and Outcome Studies, Discipline of Medicine, 122 Frome Street, Adelaide, South Australia, 5000, Australia.
出版信息
Bone Joint Res. 2012 May 1;1(5):93-8. doi: 10.1302/2046-3758.15.2000039. Print 2012 May.
OBJECTIVES
To assess the sensitivity and specificity of self-reported osteoporosis compared with dual energy X-ray absorptiometry (DXA) defined osteoporosis, and to describe medication use among participants with the condition.
METHODS
Data were obtained from a population-based longitudinal study and assessed for the prevalence of osteoporosis, falls, fractures and medication use. DXA scans were also undertaken.
RESULTS
Overall 3.8% (95% confidence interval (CI) 3.2 to 4.5) of respondents and 8.8% (95% CI 7.5 to 10.3) of those aged ≥ 50 years reported that they had been diagnosed with osteoporosis by a doctor. The sensitivity (those self-reporting osteoporosis and having low bone mineral density (BMD) on DXA) was low (22.7%), although the specificity was high (94.4%). Only 16.1% of those aged ≥ 50 years and with DXA-defined osteoporosis were taking bisphosphonates.
CONCLUSIONS
The sensitivity of self-reporting to identify osteoporosis is low. Anti-osteoporotic medications are an important part of osteoporosis treatment but opportunities to use appropriate medications were missed and inappropriate medications were used.
目的
评估与双能 X 射线吸收法（DXA）定义的骨质疏松症相比，自我报告的骨质疏松症的敏感性和特异性，并描述该疾病患者的药物使用情况。
方法
数据来自基于人群的纵向研究，评估了骨质疏松症、跌倒、骨折和药物使用的患病率。还进行了 DXA 扫描。
结果
总体而言，3.8%（95%置信区间（CI）3.2 至 4.5）的受访者和 8.8%（95% CI 7.5 至 10.3）的年龄≥50 岁的受访者报告说他们曾被医生诊断患有骨质疏松症。自我报告患有骨质疏松症且 DXA 检查显示骨密度低（BMD）的患者的敏感性（22.7%）较低，尽管特异性（94.4%）较高。仅 16.1%的年龄≥50 岁且 DXA 定义为骨质疏松症的患者服用双膦酸盐。
结论
自我报告骨质疏松症的敏感性较低。抗骨质疏松症药物是骨质疏松症治疗的重要组成部分，但错过了使用适当药物的机会，并使用了不适当的药物。
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