Waikato Clinical School, University of Auckland, Hamilton, New Zealand.
J Med Screen. 2013 Mar;20(1):49-51. doi: 10.1177/0969141313485729. Epub 2013 May 13.
To ascertain the rates and patterns of prostate-specific antigen (PSA) screening in New Zealand men.
The study population included 35,958 men aged 40+ years, with no prior diagnosis of prostate cancer, enrolled in 31 general practices in the Midland Cancer Network Region of New Zealand in 2010. Computerized practice records were searched for information, including reasons for testing, for men with elevated PSA test results in 2010. PSA results for 2007-2010 were obtained from community laboratories. Screened men were identified and screening rates calculated by age.
Of 9344 men who underwent one or more PSA tests in 2010, 84.9% were classified as having been screened. The overall screening rate was 22.1%, with 24.4% of men aged 70+ years screened. Elevated PSA levels were found in 2.1% of screened men. Of the men screened in 2010, 57.3% had had a screening test in the previous three years.
General practitioners in New Zealand commonly screen men (including those aged 70+) for prostate cancer, despite the lack of trial evidence that these men would benefit from screening. The value of annual PSA testing in men with previous normal PSA levels is unproven. Longer intervals between tests would be appropriate.
确定新西兰男性前列腺特异性抗原(PSA)筛查的比率和模式。
研究人群包括 2010 年在新西兰米德兰癌症网络地区的 31 家普通诊所登记的 35958 名年龄在 40 岁以上、无前列腺癌既往诊断的男性。计算机化的实践记录被搜索信息,包括在 2010 年 PSA 测试结果升高的男性的测试原因。2007-2010 年的 PSA 结果从社区实验室获得。确定筛查男性,并按年龄计算筛查率。
在 2010 年接受过一次或多次 PSA 检测的 9344 名男性中,84.9%被归类为接受过筛查。总的筛查率为 22.1%,70 岁以上男性的筛查率为 24.4%。筛查男性中,2.1%的 PSA 水平升高。在 2010 年接受筛查的男性中,57.3%的人在过去三年中进行了筛查测试。
尽管缺乏试验证据表明这些男性会从筛查中受益,但新西兰的全科医生通常会对男性(包括 70 岁以上的男性)进行前列腺癌筛查。在之前 PSA 水平正常的男性中,每年进行 PSA 检测的价值尚未得到证实。更长的检测间隔将是合适的。