子痫前期的患病率受艾滋病毒/艾滋病影响吗？一项回顾性病例对照研究。
Is the prevalence of pre-eclampsia affected by HIV/AIDS? A retrospective case-control study.
作者信息
Kalumba V M S, Moodley J, Naidoo T D
机构信息
Department of Obstetrics and Gynaecology, Pietermaritzburg Complex of Academic Hospitals; Women's Health and HIV Research Group, Department of Obstetrics and Gynaecology, University of KwaZulu-Natal, Durban, South Africa.
出版信息
Cardiovasc J Afr. 2013 Mar;24(2):24-7. doi: 10.5830/CVJA-2012-078.
Abstract
OBJECTIVE
To evaluate the rate of HIV/AIDS (and CD4 levels) in women with pre-eclampsia compared to that of a control group.
METHODS
This was a retrospective case-control study in a tertiary and regional hospital in South Africa. We reviewed the hospital records of women who had delivered in these hospitals between 1 January 2008 and 30 June 2010. The records of women with pre-eclampsia during the study period were analysed. Their HIV infection rate was compared to that of a control group consisting of normotensive healthy pregnant women.
RESULTS
Among 492 cases of pre-eclampsia, 130 (26.4%) were HIV infected. In the control group, 183/500 (36.6%) were HIV infected (p = 0.001, OR = 0.62, 95% CI: 0.47-0.82). After adjustment to match the difference in maternal age and parity, the rate of HIV/AIDS was lower in the pre-eclamptic group than in the control group (p = 0.005, OR = 0.658).
CONCLUSION
The rate of HIV/AIDS was significantly lower in women with pre-eclampsia than in normotensive healthy pregnant women.
摘要
目的
评估子痫前期女性中艾滋病毒/艾滋病感染率（及CD4水平），并与对照组进行比较。
方法
这是一项在南非一家三级区域医院开展的回顾性病例对照研究。我们查阅了2008年1月1日至2010年6月30日期间在这些医院分娩的女性的医院记录。分析了研究期间子痫前期女性的记录。将她们的艾滋病毒感染率与由血压正常的健康孕妇组成的对照组进行比较。
结果
在492例子痫前期病例中，130例（26.4%）感染了艾滋病毒。在对照组中，183/500例（36.6%）感染了艾滋病毒（p = 0.001，OR = 0.62，95%CI：0.47 - 0.82）。在调整以匹配产妇年龄和胎次差异后，子痫前期组的艾滋病毒/艾滋病感染率低于对照组（p = 0.005，OR = 0.658）。
结论
子痫前期女性的艾滋病毒/艾滋病感染率显著低于血压正常的健康孕妇。
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