DNA 机器对酶级联反应的调控。
Regulation of an enzyme cascade reaction by a DNA machine.
机构信息
Key Laboratory of Organic Optoelectronics & Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing 100084, China.
出版信息
Small. 2013 Sep 23;9(18):3088-91. doi: 10.1002/smll.201300019. Epub 2013 Apr 24.
PMID:23613449
Abstract
A strategy for the regulation of enzyme cascade reaction efficiency by a DNA machine in vitro is presented. Two cascade enzymes (GOx and HRP) are attached to the DNA machine, and the enzyme cascade reaction shows much higher efficiency when the two enzymes are brought closer by the DNA machine than when they are distant.
摘要
提出了一种通过 DNA 机器在体外调节酶级联反应效率的策略。两种级联酶（GOx 和 HRP）被连接到 DNA 机器上，当两种酶被 DNA 机器拉近时，酶级联反应的效率比它们相距较远时高得多。
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