McMonnies Charles W
School of Optometry and Vision Science, University of New South Wales, Kensington, New South Wales, Australia.
Clin Exp Optom. 2013 Mar;96(2):197-200. doi: 10.1111/j.1444-0938.2012.00726.x.
The aim was to describe the baropathic nature of the keratectasias and to examine the possible significance of intraocular pressure-elevating activities in the development and/or progression of these conditions.
Articles were selected from 150 produced from a PubMed search for keratectasias and used to elucidate the biomechanics and dependence on intraocular pressure of those conditions.
The combination of viscoelastic and baropathic features of keratectasia indicate that elevations in intraocular pressure have the potential to contribute to the development and/or progression of these conditions. Acute events such as hydrops and perforation appear to be more or less dependent on IOP elevation.
Development and/or progression of keratectasia might be slowed by patient counselling, which explains the dependence of keratectasia on intraocular pressure and recommends avoidance and/or moderation of activities that elevate intraocular pressure. Successful adoption of such advice could reduce rates of disease progression and the need for refitting with more expensive contact lens designs, which are often required for advanced cases, as well as reduce the need for grafting and the drain on limited availability of donor corneas.
目的是描述角膜扩张症的气压性本质,并探讨眼压升高活动在这些病症的发生和/或进展中的可能意义。
从PubMed搜索角膜扩张症产生的150篇文章中进行筛选,用于阐明这些病症的生物力学以及对眼压的依赖性。
角膜扩张症的粘弹性和气压性特征表明,眼压升高有可能促进这些病症的发生和/或进展。诸如角膜水肿和穿孔等急性事件似乎或多或少依赖于眼压升高。
通过对患者进行咨询,可能会减缓角膜扩张症的发生和/或进展,这解释了角膜扩张症对眼压的依赖性,并建议避免和/或适度进行眼压升高的活动。成功采纳此类建议可降低疾病进展率,减少为晚期病例常需的更昂贵隐形眼镜设计重新配镜的需求,以及减少移植需求和对有限供体角膜供应的消耗。