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使用动态Scheimpflug分析仪评估准分子激光原位角膜磨镶术（LASIK）后圆锥角膜患者的角膜生物力学。

Evaluation of corneal biomechanics in patients with keratectasia following LASIK using dynamic Scheimpflug analyzer.

作者信息

Ueki Ryotaro, Maeda Naoyuki, Fuchihata Mutsumi, Asai Tomoko, Koh Shizuka, Fujimoto Hisataka, Uematsu Masafumi, Nishida Kohji

机构信息

Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.

出版信息

Jpn J Ophthalmol. 2018 Jul;62(4):443-450. doi: 10.1007/s10384-018-0594-5. Epub 2018 Apr 26.

DOI:10.1007/s10384-018-0594-5
PMID:29700642
Abstract

PURPOSE

To investigate the corneal biomechanics in eyes with keratectasia following LASIK using a dynamic Scheimpflug analyzer.

DESIGN

Case-Control study.

METHOD

The subjects in the study included 12 eyes with keratectasia after LASIK (KE), 24 eyes with keratoconus (KC), 17 eyes without keratectasia after LASIK (LASIK), and 34 eyes with normal corneas (Normal). Corneal biomechanics of the four groups were evaluated using a dynamic Scheimpflug analyzer.

RESULTS

Compared with Normal (7.06 ± 0.54), the radius at the highest concavity (radius, mm) of LASIK (5.96 ± 0.76), KE (4.93 ± 0.61) and KC (5.39 ± 1.02) were significantly small. The Deflection Amplitude (HCDLA, mm) of Normal (0.94 ± 0.07) was significantly lower than those of KE (1.11 ± 0.10) and KC (1.06 ± 0.16), and was not significantly different from that of LASIK (0.98 ± 0.07). There were significant differences between LASIK and KE in radius and HCDLA (P < 0.05), whereas KE and KC had no differences in these parameters.

CONCLUSIONS

Corneal biomechanical features evaluated using the dynamic Scheimpflug analyzer suggest that biomechanical properties in eyes with keratectasia, keratoconus, and LASIK are different from those of normal eyes. Although the biomechanics in eyes with keratectasia differs from that in eyes with LASIK, it is similar to that in eyes with keratoconus.

摘要

目的

使用动态Scheimpflug分析仪研究准分子激光原位角膜磨镶术（LASIK）后圆锥角膜眼中的角膜生物力学。

设计

病例对照研究。

方法

研究对象包括12只LASIK术后圆锥角膜（KE）眼、24只圆锥角膜（KC）眼、17只LASIK术后无圆锥角膜（LASIK）眼和34只正常角膜（正常）眼。使用动态Scheimpflug分析仪评估四组的角膜生物力学。

结果

与正常组（7.06±0.54）相比，LASIK组（5.96±0.76）、KE组（4.93±0.61）和KC组（5.39±1.02）最高凹陷处的半径（单位：mm）明显较小。正常组的偏转幅度（HCDLA，单位：mm）（0.94±0.07）明显低于KE组（1.11±0.10）和KC组（1.06±0.16），与LASIK组（0.98±0.07）无明显差异。LASIK组和KE组在半径和HCDLA方面存在显著差异（P<0.05），而KE组和KC组在这些参数上无差异。

结论

使用动态Scheimpflug分析仪评估的角膜生物力学特征表明，圆锥角膜、圆锥角膜和LASIK眼中的生物力学特性与正常眼不同。虽然圆锥角膜眼中的生物力学与LASIK眼中的不同，但与圆锥角膜眼中的相似。

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