Arechaga Ignacio
Departamento de Biología Molecular, Universidad de Cantabria e Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC), UC-CSIC-SODERCAN, Santander, Spain.
J Mol Microbiol Biotechnol. 2013;23(1-2):13-23. doi: 10.1159/000346515. Epub 2013 Apr 18.
Nonphotosynthetic bacteria generally lack intracellular membranes (ICMs). However, large scale overproduction of membrane proteins in Escherichia coli can be accompanied by a massive proliferation of new ICMs in the cytoplasm. In some cases, like in the overexpression of the ATP synthase b subunit in E. coli, the morphology of these internal invaginations resembles that of the inner mitochondrial cristae. Moreover, the new ICMs have a higher content in cardiolipin than the bacterial inner and outer membranes. This review covers the features that seem to apply to membrane proliferation in bacteria and highlights the similarities with those behind the formation of the mitochondrial inner cristae.
非光合细菌通常缺乏细胞内膜（ICM）。然而，在大肠杆菌中大规模过量生产膜蛋白时，细胞质中可能会伴随着新的细胞内膜大量增殖。在某些情况下，比如在大肠杆菌中过量表达ATP合酶β亚基时，这些内部内陷的形态类似于线粒体内嵴。此外，新的细胞内膜中的心磷脂含量高于细菌的内膜和外膜。本综述涵盖了似乎适用于细菌膜增殖的特征，并强调了与线粒体内嵴形成背后特征的相似性。
