Ruzza Andrea, Czer Lawrence S C, Trento Alfredo, Esmailian Fardad
Division of Cardiothoracic Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA.
Interact Cardiovasc Thorac Surg. 2013 Aug;17(2):416-8. doi: 10.1093/icvts/ivt172. Epub 2013 Apr 24.
Combined heart and kidney transplantation is increasing in frequency but there are no guidelines to establish the indications, contraindications and sequence for this surgical procedure. We report our single-centre experience on 30 consecutive patients who underwent combined heart and kidney transplant in comparison with heart transplant alone. Patients had similar preoperative characteristics in both groups. Combined heart and kidney transplant is associated with the same long-term survival rate, low cellular rejection and antibody-mediated rejection rates when compared with heart transplant alone. We did not observe any difference in the outcomes related to preoperative patient characteristics. We suggest the staged surgical approach as the preferred method for transplant.
心脏和肾脏联合移植的频率正在增加，但对于该手术的适应证、禁忌证及手术顺序尚无指导原则。我们报告了连续30例接受心脏和肾脏联合移植患者的单中心经验，并与单纯心脏移植患者进行了比较。两组患者术前特征相似。与单纯心脏移植相比，心脏和肾脏联合移植的长期生存率、细胞性排斥反应及抗体介导的排斥反应发生率相同。我们未观察到术前患者特征对预后有任何差异。我们建议采用分期手术方法作为移植的首选方法。
