Norman J C, Brook M I, Cooley D A, Klima T, Kahan B D, Frazier O H, Keats A S, Hacker J, Massin E K, Duncan J M, Solis R T, Dacso C C, Luper W E, Winston D S, Reul G J
Lancet. 1978 May 27;1(8074):1125-7. doi: 10.1016/s0140-6736(78)90301-x.
A patient with acute bacterial endocarditis in whom ischaemic contracture of the left ventricle (stone-heart syndrome) developed during aortic and mitral valve replacement had an emergency implantation of an intracorporeal partial artificial heart (an abdominal left-ventricular assist device of ALVAD). This device functioned as a total artificial heart for nearly 6 days, while a donor heart for transplantation was sought. The ALVAD was then removed, and the patient received allografts of a heart and a kidney. The transplanted heart functioned well, but the patient died 15 days later from gram-negative sepsis. There was no evidence of cardiac or renal allograft rejection.
一名患有急性细菌性心内膜炎的患者,在进行主动脉瓣和二尖瓣置换术期间发生了左心室缺血性挛缩(石心综合征),紧急植入了体内部分人工心脏(腹部左心室辅助装置,ALVAD)。该装置作为全人工心脏运行了近6天,同时寻找供体心脏进行移植。然后移除了ALVAD,患者接受了心脏和肾脏的同种异体移植。移植的心脏功能良好,但患者在15天后死于革兰氏阴性菌败血症。没有心脏或肾脏同种异体移植排斥的证据。