Bioresources Research Unit, National Center for Genetic Engineering and Biotechnology (BIOTEC), Klong Luang, Pathumthani, Thailand.
J Fluoresc. 2013 Sep;23(5):853-7. doi: 10.1007/s10895-013-1216-8. Epub 2013 Apr 25.
Diimine ligand (DL) 1 significantly exhibited the fluorescence quenching upon binding to guanine. Changing at the para-substituent of the phenyl ring from the hydroxyl to bromo groups reversely enhanced the fluorescence in the presence of guanine. The reverse in the fluorescence selectivity indicated the profound effect of the substituent at the para-position of the phenyl ring. The simple synthesis of DL 1 and DL 2 with good selectivity for guanine offers these DLs as promising compounds for chemosensors of other guanine derivatives.
二亚胺配体（DL）1 与鸟嘌呤结合时，显著表现出荧光猝灭。当苯环的对位取代基由羟基变为溴原子时，在存在鸟嘌呤的情况下，荧光反而增强。荧光选择性的反转表明苯环对位取代基的巨大影响。DL 1 和 DL 2 的简单合成具有对鸟嘌呤的良好选择性，为这些 DL 作为其他鸟嘌呤衍生物化学传感器的有前途的化合物提供了可能。
