Ranario Jennifer C, Reddick Claire S, Peterson Jennifer D, Smith Jennifer L
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, USA.
Cutis. 2013 Mar;91(3):137-40.
Candidiasis is the most common fungal infection in immunocompromised patients who are at greater risk for developing disseminated disease. Renal transplant recipients often are administered immunosuppressants and therefore are at an increased risk for developing disseminated candidal infections. Disseminated candidiasis generally does not present with cutaneous lesions, but when present, lesions usually are generalized or limited to the trunk and limbs. We describe the case of an immunosuppressed renal transplant recipient who developed a disseminated Candida kefyr infection and presented with oral mucosal lesions and cutaneous lesions limited to the left lower extremity. The lesions were localized due to a thrombus that was subsequently found in the patient's left external iliac artery.
念珠菌病是免疫功能低下患者中最常见的真菌感染,这类患者发生播散性疾病的风险更高。肾移植受者常使用免疫抑制剂,因此发生播散性念珠菌感染的风险增加。播散性念珠菌病通常无皮肤损害,但出现时,损害通常为全身性或局限于躯干和四肢。我们描述了一例免疫抑制的肾移植受者,其发生播散性克菲念珠菌感染,并出现口腔黏膜损害和仅局限于左下肢的皮肤损害。这些损害因随后在患者左髂外动脉发现的血栓而局限化。