Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
Am J Addict. 2013 May-Jun;22(3):271-6. doi: 10.1111/j.1521-0391.2012.12002.x.
The present study evaluated changes in rates of self-reported heroin and cocaine use in opioid-dependent individuals newly registered to a syringe exchange program (SEP), and examined the effects of recovery-oriented longitudinal variables (i.e., substance abuse treatment, self-help group participation, employment) on changes in drug use.
Study participants (n = 240) were opioid-dependent and drawn from a larger study evaluating strategies to improve treatment-seeking. Mixed model analyses were used to evaluate changes in rates of heroin and cocaine use, and longitudinal correlates of change in these substances, over a one-year period.
Results showed reductions in days of heroin and cocaine use over time, and that participation in recovery-oriented activities was strongly associated with greater changes in drug use.
These results suggest SEPs can play a vital role in facilitating reductions in drug use through motivating participation in treatment and other recovery-oriented activities.
本研究评估了新登记到注射毒品者共用针具交换项目（SEP）的阿片类药物依赖者中自我报告的海洛因和可卡因使用率的变化，并考察了以康复为导向的纵向变量（即药物滥用治疗、自助团体参与、就业）对药物使用变化的影响。
研究参与者（n=240）为阿片类药物依赖者，来自一项评估改善治疗寻求策略的更大研究。采用混合模型分析评估了在一年期间内，海洛因和可卡因使用率的变化，以及这些物质变化的纵向相关性。
结果显示，随着时间的推移，海洛因和可卡因的使用天数减少，并且参与以康复为导向的活动与药物使用的更大变化密切相关。
这些结果表明，SEP 通过促使参与治疗和其他以康复为导向的活动，在促进减少药物使用方面可以发挥重要作用。
