University Hospital of Psychiatry Bern, Bolligenstrasse 111, Bern, Switzerland.
Am J Addict. 2013 May-Jun;22(3):292-6. doi: 10.1111/j.1521-0391.2012.12000.x.
BACKGROUND/AIM: Adult Alcohol Use Disorders (AUD) patients with Attention Deficit/Hyperactivity Disorder (ADHD) symptoms may suffer more from craving than patients who only have AUD. However, craving may be even more strongly related to withdrawal and psychiatric symptoms; therefore, the association between craving and ADHD may be misinterpreted. The purpose of this study is to examine the association between craving and ADHD symptoms among AUD patients in more detail.
In a multisite study, 385 patients with and without ADHD symptoms who were attending treatment for alcohol dependence were compared in terms of craving, withdrawal, and psychiatric symptoms. The contribution of ADHD symptoms to craving was estimated in a hierarchical regression analysis by controlling for psychiatric and withdrawal symptoms.
Patients with probable adult ADHD showed higher craving, more withdrawal and psychiatric symptoms, and rated withdrawal symptoms as more severe than did patients without ADHD symptoms. In the regression model, only about 3% of variance in alcohol craving was explained by ADHD symptomatology, whereas 23% of the variance was explained when withdrawal and psychiatric symptoms were added to the model.
Alcohol craving is likely related to withdrawal and psychiatric symptoms more strongly than to ADHD symptoms.
背景/目的:有注意缺陷多动障碍(ADHD)症状的成年酒精使用障碍(AUD)患者可能比仅患有 AUD 的患者更易受渴望的影响。然而,渴望可能与戒断和精神症状的关系更密切;因此,渴望和 ADHD 之间的关联可能会被误解。本研究的目的是更详细地研究 AUD 患者中渴望和 ADHD 症状之间的关联。
在一项多中心研究中,比较了 385 名有和无 ADHD 症状的正在接受酒精依赖治疗的患者,比较了他们的渴望、戒断和精神症状。通过控制精神和戒断症状,在分层回归分析中估计 ADHD 症状对渴望的贡献。
患有成人 ADHD 可能性的患者表现出更高的渴望、更多的戒断和精神症状,并且比没有 ADHD 症状的患者更严重地评估戒断症状。在回归模型中,ADHD 症状仅解释了酒精渴望的约 3%的方差,而当将戒断和精神症状添加到模型中时,解释了 23%的方差。
酒精渴望可能与戒断和精神症状的关系比与 ADHD 症状的关系更密切。