Department of Analytical and Bioanalytical Sciences and Miniaturization, UMR ESPCI ParisTech-CNRS-UPMC PECSA 7195, ESPCI ParisTech, Paris, France.
Talanta. 2013 Jun 15;110:128-34. doi: 10.1016/j.talanta.2013.02.023. Epub 2013 Feb 18.
A powerful analytical method for the determination of the family of the nitro musk compounds at trace level in environmental waters-river, sea, and water from a treatment plant-is presented. The method is based on the use of molecularly imprinted silica (MIS) as sorbent for solid phase extraction (SPE) used for the clean-up and the concentration step of the target analytes previous to their determination by gas chromatography-mass spectrometry. The optimized extraction procedure allowed extraction recoveries between 61% and 87% using the MIS. The comparison with a non-imprinted silica (NIS) sorbent, for which extraction recoveries between 8% and 26% were obtained, showed the high selectivity of the MIS for the nitro musks. Moreover, high enrichment factors, ranging between 580 and 827, were achieved. The imprinted sorbent was compared to a conventional polymeric SPE sorbent for the extraction of the target compounds from environmental waters, showing high selectivity of the MIS and its clean-up potential. For the first time, the five nitro musk compounds were selectively extracted with an imprinted material.
本文提出了一种在痕量水平上测定环境水中（河流、海洋和污水处理厂水）硝基麝香化合物家族的强大分析方法。该方法基于使用分子印迹硅胶（MIS）作为固相萃取（SPE）的吸附剂，用于目标分析物的净化和浓缩步骤，然后通过气相色谱-质谱法进行测定。优化的提取程序允许使用 MIS 进行 61%至 87%的提取回收率。与提取回收率在 8%至 26%之间的非印迹硅胶（NIS）吸附剂进行比较，表明 MIS 对硝基麝香具有高选择性。此外，还实现了 580 至 827 之间的高富集因子。将印迹吸附剂与用于从环境水中提取目标化合物的常规聚合物 SPE 吸附剂进行了比较，结果表明 MIS 具有高选择性及其净化潜力。这是首次使用印迹材料选择性提取五种硝基麝香化合物。
