Xue Ru, Wang Mo, Li Qiu, Zhao Xiao Dong, Tang Xue Mei, Shi Ji Sheng, He Ling, Wang Qiao, Wang Shan, Luo Xiao Ping
Laboratory of Clinical Immunology, Institute of Children Pediatric Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Clin Nephrol. 2013 May;79(5):407-13. doi: 10.5414/cn107531.
With an incidence ranging from 0.01% to 1.0%, renal artery pseudoaneurysm (RAP) is a rare complication after renal biopsy, percutaneous renal surgery, penetrating trauma, and rarely blunt renal trauma.
Percutaneous renal biopsy (PRB) of native kidneys was performed in 1,500 pediatric patients under real-time ultrasonographic guidance at our institution from July 1999 to January 2011. A retrospective review of these cases revealed that 2 patients developed a post-biopsy RAP. The diagnosis of RAP was established using color duplex ultrasonography (US), contrast-enhanced computed tomography (CT) and digital substraction angiography (DSA).
Two patients developed RAP after 1,500 PRBs were performed (0.13% incidence). In the presented cases, immediate post-bioptic ultrasound showed no abnormalities. A high index of suspicion for RAP was prompted when complications such as unexplained gross hematuria and anemia occurred and the arterial phase of CT showed a well-circumscribed hyperdense area with a contrast enhancement similar to the adjacent arterial vessels. The diagnosis was confirmed by DSA and then the feeding artery of RAP was successfully occluded. After the procedure, the patients recovered and were discharged shortly.
RAP is a rare, but potentially life-threatening complication after PRB and can be treated successfully with superselective arterial embolization.
肾动脉假性动脉瘤(RAP)是肾活检、经皮肾手术、穿透性创伤后罕见的并发症,钝性肾创伤后则更为罕见,其发病率在0.01%至1.0%之间。
1999年7月至2011年1月期间,在我们机构对1500例儿科患者进行了实时超声引导下的经皮肾活检(PRB)。对这些病例的回顾性研究发现,有2例患者在活检后发生了RAP。通过彩色双功超声(US)、对比增强计算机断层扫描(CT)和数字减影血管造影(DSA)确诊RAP。
1500例PRB术后有2例发生RAP(发病率为0.13%)。在本病例中,活检后立即进行的超声检查未发现异常。当出现不明原因的肉眼血尿和贫血等并发症,且CT动脉期显示有边界清晰的高密度区域,其对比增强与相邻动脉血管相似时,应高度怀疑RAP。DSA确诊后,成功闭塞了RAP的供血动脉。术后,患者恢复良好并很快出院。
RAP是PRB术后罕见但可能危及生命的并发症,可通过超选择性动脉栓塞成功治疗。