Salemis Nikolaos S, Nakos Georgios, Tsiambas Evangelos, Tsantilas Vlasios, Seretis Charalambos
Breast Surgery Unit, Army General Hospital, Athens, Greece.
Breast Dis. 2012;34(1):29-34. doi: 10.3233/BD-130347.
Myofibroblastoma of the breast (MFB) is a rare benign tumor of mesenchymal origin with only 80 cases reported in the literature so far. It most commonly occurs in elderly males and postmenopausal females and grows slowly over a period of months to years. In this study we describe a very rare case of a MFB in a premenopausal woman who presented with a rapidly growing breast mass. Diagnostic evaluation and management of the patient are discussed along with a review of the literature. We conclude that despite its rarity, myofibroblastoma should always be considered in the differential diagnosis of mesenchymal breast tumors. No specific imaging features have been described. Thorough immunohistochemical analysis is crucial to obtain a definitive diagnosis. Local excision is the treatment of choice.
乳腺肌纤维母细胞瘤（MFB）是一种罕见的间叶源性良性肿瘤，迄今为止文献中仅报道了80例。它最常见于老年男性和绝经后女性，在数月至数年的时间里生长缓慢。在本研究中，我们描述了一例非常罕见的绝经前女性乳腺肌纤维母细胞瘤病例，该患者表现为乳腺肿块迅速增大。本文讨论了该患者的诊断评估和治疗，并对文献进行了综述。我们得出结论，尽管乳腺肌纤维母细胞瘤罕见，但在间叶性乳腺肿瘤的鉴别诊断中应始终予以考虑。目前尚未描述其特异性影像学特征。全面的免疫组化分析对于明确诊断至关重要。局部切除是首选的治疗方法。
