Department of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, People's Republic of China.
Heart Lung Circ. 2013 Aug;22(8):612-7. doi: 10.1016/j.hlc.2013.03.084. Epub 2013 Apr 22.
To compare six risk scores with regard to their validity to predict in-hospital mortality after heart valve surgery in a single-centre patient population of China.
From January 2006 to December 2011, 3479 consecutive patients who underwent heart valve surgery at our centre were collected and scored according to the EuroSCORE II, VA risk score, NNE risk score, Ambler risk score, NYC risk score, and STS risk score. Calibration of the six risk scores was assessed by the Hosmer-Lemeshow (H-L) test. Discrimination was tested by calculating the area under the receiver operating characteristic (ROC) curve.
Observed mortality was 3.32% overall. The STS score showed good calibration in predicting in-hospital mortality (H-L: P = 0.126). The EuroSCORE II, VA score, NNE score, and NYC score underpredicted observed mortality (H-L: P < 0.0001, P < 0.0001, P = 0.001, and P < 0.0001, respectively) and the Ambler score overpredicted observed mortality (H-L: P = 0.005). The discriminative power (i.e. the area under the ROC curve) for in-hospital mortality was highest for the STS score (0.706), followed by the EuroSCORE II model (0.693), NNE score (0.684), NYC score (0.682), Ambler score (0.677) and VA score (0.643).
Compared with the EuroSCORE II, VA score, NNE score, NYC score, and the Ambler score, the STS score gives an accurate prediction for individual operative risk in patients undergoing heart valve surgery at our centre. Therefore, the use of the STS score for risk evaluation maybe suitable in patients undergoing heart valve surgery at our centre in the future.
比较 6 种风险评分模型,以评估它们在中国单中心人群中预测心脏瓣膜手术后院内死亡率的准确性。
从 2006 年 1 月至 2011 年 12 月,我们中心连续收集了 3479 例接受心脏瓣膜手术的患者,根据欧洲心脏手术风险评分 II(EuroSCORE II)、VA 风险评分、NNE 风险评分、Ambler 风险评分、NYC 风险评分和 STS 风险评分进行评分。通过 Hosmer-Lemeshow(H-L)检验评估 6 种风险评分模型的校准程度。通过计算受试者工作特征(ROC)曲线下面积来检验区分度。
总体观察死亡率为 3.32%。STS 评分在预测院内死亡率方面具有较好的校准能力(H-L:P = 0.126)。EuroSCORE II、VA 评分、NNE 评分和 NYC 评分低估了观察死亡率(H-L:P < 0.0001、P < 0.0001、P = 0.001 和 P < 0.0001),而 Ambler 评分高估了观察死亡率(H-L:P = 0.005)。STS 评分对院内死亡率的判别能力(即 ROC 曲线下面积)最高(0.706),其次是 EuroSCORE II 模型(0.693)、NNE 评分(0.684)、NYC 评分(0.682)、Ambler 评分(0.677)和 VA 评分(0.643)。
与 EuroSCORE II、VA 评分、NNE 评分、NYC 评分和 Ambler 评分相比,STS 评分能更准确地预测我们中心接受心脏瓣膜手术患者的个体手术风险。因此,STS 评分可能适合未来我们中心接受心脏瓣膜手术患者的风险评估。