Toyama T, Yokoyama I, Nishi K
Eur J Pharmacol. 1975 Mar;31(1):63-71. doi: 10.1016/0014-2999(75)90079-5.
Electrical activity of the dog's esophagus was evoked by electrical stimulation of the vagus nerve and recorded by using a suction electrode placed on the serosal surface of the esophagus. Neuromuscular blocking agents (d-tubocurarine and succinylcholine) blocked this activity, while atropine had no effect. Hexamethonium (in doses which did not effect neuromuscular transmission in the diaphragm) and high doses of nicotine significantly depressed the evoked esophageal electrical activity, while lower doses of nicotine facilitated the response. The results suggest that a certain proportion of the striated muscle of the esophagus is innervated by processes from the intermediate ganglion cells in the Auerbach plexus.
通过电刺激迷走神经诱发犬食管的电活动，并使用置于食管浆膜表面的吸引电极进行记录。神经肌肉阻滞剂（d - 筒箭毒碱和琥珀酰胆碱）可阻断这种活动，而阿托品则无作用。六甲铵（剂量不影响膈肌神经肌肉传递）和高剂量尼古丁显著抑制诱发的食管电活动，而低剂量尼古丁则增强反应。结果表明，食管的一定比例横纹肌由奥尔巴赫神经丛中间神经节细胞的突起支配。
