School of Social Work, University of Pittsburgh, 2117 Cathedral of Learning, Pittsburgh, PA, 15260, USA,
J Autism Dev Disord. 2013 Dec;43(12):2866-77. doi: 10.1007/s10803-013-1834-7.
Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to investigate its feasibility, acceptability, and initial efficacy in treating these impairments. Results indicated that CET was satisfying to participants, with high treatment attendance and retention. Effects on cognitive deficits and social behavior were also large (d = 1.40-2.29) and statistically significant (all p < .001). These findings suggest that CET is a feasible, acceptable, and potentially effective intervention for remediating the social and non-social cognitive impairments in verbal adults with autism.
自闭症成年人在社交和非社交信息处理方面存在明显障碍，但目前针对这些障碍的治疗方法却很少。本研究对 14 名患有自闭症谱系障碍的语言障碍成年人进行了为期 18 个月的非对照认知增强治疗（CET）试验，以调查其治疗这些障碍的可行性、可接受性和初步疗效。结果表明，CET 令参与者非常满意，其治疗出席率和保留率都很高。认知缺陷和社交行为的改善效果也很大（d=1.40-2.29），且具有统计学意义（所有 p<0.001）。这些发现表明，CET 是一种可行、可接受且可能有效的干预措施，可用于改善自闭症语言障碍成年人的社交和非社交认知障碍。
