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依托芬那酯局部应用的不良反应:瘀点疹。

Adverse reaction of topical etofenamate: petechial eruption.

作者信息

Orbak Z, Yildirim Z K, Sepetci O, Karakelleoglu C, Alp H

机构信息

Department of Paediatric Endocrinology and Metabolism, Atatürk University, Faculty of Medicine, Erzurum, Turkey.

出版信息

West Indian Med J. 2012 Oct;61(7):767-9.

PMID:23620980
Abstract

Etofenamate is a non-steroidal anti-inflammatory drug (NSAID). Clinical findings caused by etofenamate are uncommon. Allergic contact dermatitis is the most common cutaneous reaction reported. But petechial eruption due to etofenamate had not been reported yet. This report concerns an 11-year old male with petechial eruption after application of topical etofenamate. Physicians need to be aware that patients can develop an asymptomatic purpuric eruption when etofenamate is ordered.

摘要

依托芬那酯是一种非甾体抗炎药(NSAID)。依托芬那酯引起的临床症状并不常见。过敏性接触性皮炎是报告中最常见的皮肤反应。但尚未有依托芬那酯引起瘀点疹的报道。本报告涉及一名11岁男性,在局部应用依托芬那酯后出现瘀点疹。医生需要意识到,当开具依托芬那酯处方时,患者可能会出现无症状紫癜疹。

相似文献

1
Adverse reaction of topical etofenamate: petechial eruption.依托芬那酯局部应用的不良反应:瘀点疹。
West Indian Med J. 2012 Oct;61(7):767-9.
2
Combined contact and photocontact allergic dermatitis to etofenamate in flogoprofen gel.氟洛芬凝胶中依托芬那酯引起的联合接触性和光接触性过敏性皮炎。
Am J Contact Dermat. 2001 Dec;12(4):215-6.
3
[Allergic contact dermatitis caused by etofenamate].[依托芬那酯引起的变应性接触性皮炎]
Z Hautkr. 1988 Jun 15;63(6):475-8.
4
Allergic contact dermatitis to etofenamate. Cross-reaction to other nonsteroidal anti-inflammatory drugs.依托芬那酯引起的变应性接触性皮炎。与其他非甾体抗炎药的交叉反应。
Contact Dermatitis. 2008 Feb;58(2):118-9. doi: 10.1111/j.1600-0536.2007.01190.x.
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Allergic and photoallergic contact dermartitis from etofenamate: study of 14 cases.
Contact Dermatitis. 2009 Aug;61(2):118-20. doi: 10.1111/j.1600-0536.2009.01565.x.
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[Hairy cell leukaemia diagnosed in a polysensitized patient with atypical haemorrhagic skin lesions].[一名多药致敏患者伴非典型出血性皮肤病变诊断为毛细胞白血病]
Orv Hetil. 2020 Sep;161(38):1646-1651. doi: 10.1556/650.2020.31831.
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Prolonged localized photosensitivity following allergic and photo-aggravated contact dermatitis from etofenamate.依托芬那酯引起的过敏性和光加重性接触性皮炎后的长期局部光敏反应。
Photodermatol Photoimmunol Photomed. 2014 Dec;30(6):340-2. doi: 10.1111/phpp.12130. Epub 2014 Aug 13.
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Allergic contact dermatitis from etofenamate: report of 9 cases.依托芬那酯所致过敏性接触性皮炎:9例报告。
Contact Dermatitis. 1994 Jul;31(1):60-2. doi: 10.1111/j.1600-0536.1994.tb01917.x.
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[Anti-edema activity of a trans-cutaneous non-steroidal anti-inflammatory agent, etofenamate gel, in rats].[经皮非甾体抗炎药依托芬那酯凝胶对大鼠的抗水肿活性]
Nihon Yakurigaku Zasshi. 1982 Aug;80(2):169-82.
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Allergic contact dermatitis from etofenamate without cross-sensitization to other anthranilic acid derivatives.依托芬那酯引起的变应性接触性皮炎,对其他邻氨基苯甲酸衍生物无交叉致敏。
Dermatology. 2003;206(4):341-2. doi: 10.1159/000069949.

引用本文的文献

1
Case Report: Nicolau syndrome due to etofenamate injection.病例报告:依托芬那酯注射导致的尼科劳综合征。
F1000Res. 2017 Jun 12;6:867. doi: 10.12688/f1000research.11705.1. eCollection 2017.
2
Development and Validation of a Stability-Indicating Assay of Etofenamate by RP-HPLC and Characterization of Degradation Products.依托芬那酯反相高效液相色谱稳定性指示测定法的建立与验证及降解产物的表征
Sci Pharm. 2013 Jul 22;81(4):1017-28. doi: 10.3797/scipharm.1305-19. Print 2013 Oct-Dec.