Ducluzeau R, Vial T, Pobel D, Descotes J
Service de Médecine d'Urgence, Toxicologie Clinique et Médecine Légale, Lyon.
J Toxicol Clin Exp. 1990 Jan-Feb;10(1):37-9.
The incidence of neuropsychiatric complications is very low in patients receiving conventional doses of cimetidine or ranitidine. In this case report, the same patient presented with psychiatric symptoms successively following treatment with both histamine H2-receptor antagonists, suggesting the involvement of histamine-mediated CNS modulation.