Ranitidine is an H2-receptor antagonist that was released recently for use in the treatment of acute duodenal ulcer disease, Zollinger-Ellison syndrome, and systemic mastocytosis with gastric hypersecretion. The pharmacokinetics, efficacy, adverse effects, and clinical utility of ranitidine are presented. The drug is similar in therapeutic effect to its predecessor, cimetidine, yet has certain advantages over cimetidine in clinical applications.
雷尼替丁是一种H2受体拮抗剂，最近被批准用于治疗急性十二指肠溃疡病、卓艾综合征以及伴有胃酸分泌过多的系统性肥大细胞增多症。本文介绍了雷尼替丁的药代动力学、疗效、不良反应及临床应用。该药物在治疗效果上与其前身西咪替丁相似，但在临床应用中比西咪替丁具有某些优势。
