Fahim M, Arndt J O
Abteilung für Experimentelle Anaesthesiologie, Universität Düsseldorf, Federal Republic of Germany.
Jpn J Physiol. 1990;40(1):33-55. doi: 10.2170/jjphysiol.40.33.
We have studied the influence of left atrial receptor stimulation on arterial baroreflex control of heart rate with a view to determine the role of cardiac efferent sympathetic and parasympathetic pathways in any interaction observed. Experiments were performed on anaesthetized, artificially ventilated, and thoracotomised cats and dogs. The sensitivity of baroreflex heart rate response was found to be higher in dogs as compared to cats. Both the sympathetic and parasympathetic effects contributed to the reflex chronotropic effects observed during changes in mean arterial blood pressure. The reflex tachycardia response during left atrial receptor stimulation was more pronounced in dogs than in cats. Stimulation of left atrial receptors caused slight inhibition of the baroreflex tachycardia response and potentiation of the bradycardia response.
我们研究了左心房感受器刺激对心率的动脉压力反射控制的影响，目的是确定心脏传出交感神经和副交感神经通路在观察到的任何相互作用中的作用。实验在麻醉、人工通气并开胸的猫和狗身上进行。发现狗的压力反射心率反应敏感性高于猫。交感神经和副交感神经效应均对平均动脉血压变化期间观察到的反射性变时效应有贡献。左心房感受器刺激期间的反射性心动过速反应在狗身上比在猫身上更明显。刺激左心房感受器会轻微抑制压力反射性心动过速反应，并增强心动过缓反应。
