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昼夜温差与老年人心血管、呼吸、消化和泌尿生殖系统疾病急诊入院的关联:一项时间序列研究。

The association between diurnal temperature range and emergency room admissions for cardiovascular, respiratory, digestive and genitourinary disease among the elderly: a time series study.

机构信息

College of Atmospheric Science, Center for Meteorological Environment and Human Health, Lanzhou University, Lanzhou 730000, China.

出版信息

Sci Total Environ. 2013 Jul 1;456-457:370-5. doi: 10.1016/j.scitotenv.2013.03.023. Epub 2013 Apr 25.

DOI:10.1016/j.scitotenv.2013.03.023
PMID:23624010
Abstract

OBJECTIVES

To evaluate the short-term effect of diurnal temperature range (DTR) on emergency room (ER) admissions among elderly adults in Beijing.

METHODS

After controlling the long-time and seasonal trend, weather, air pollution and other confounding factors, a semi-parametric generalized additive model (GAM) was used to analyze the exposure-effect relationship between DTR and daily ER admissions among elderly adults with different lag structures from 2009 to 2011 in Beijing. We examined the effects of DTR for stratified groups by age and gender, and conducted the modifying effect of season on DTR to test the possible interaction.

RESULTS

Significant associations were found between DTR and four major causes of daily ER admissions among elderly adults in Beijing. A 1 °C increase in the 8-day moving average of DTR (lag 07) corresponded to an increase of 2.08% (95% CI: 0.88%-3.29%) in respiratory ER admissions and 2.14% (95% CI: 0.71%-3.59%) in digestive ER admissions. A 1 °C increase in the 3-day and 6-day moving average of DTR (lag 02 and lag 05) corresponded to a 0.76% (95% CI: 0.07%-1.46%) increase in cardiovascular ER admissions, and 1.81% (95% CI: 0.21%-3.45%) increase in genitourinary ER admissions, respectively. The people aged 75 years and older were associated more strongly with DTR than the 65-74 age group. The modifying effect of season on DTR was observed and it was various in four causes.

CONCLUSIONS

This study strengthens the evidence that DTR is an independent risk factor for ER admissions among elderly persons. Some prevention programs that target the elderly and other high risk subgroups for impending large temperature changes may reduce the impact of DTR on people's health.

摘要

目的

评估日较差(DTR)对北京老年人群急诊就诊的短期影响。

方法

在控制长期和季节性趋势、天气、空气污染和其他混杂因素后,采用半参数广义相加模型(GAM)分析了 2009 年至 2011 年北京老年人群不同滞后结构下 DTR 与每日急诊就诊之间的暴露-效应关系。我们考察了 DTR 对不同年龄和性别的分层人群的影响,并对 DTR 进行了季节修饰效应检验,以测试可能的交互作用。

结果

DTR 与北京老年人群每日急诊就诊的四个主要病因之间存在显著关联。8 天移动平均 DTR(滞后 07)每升高 1°C,与呼吸系统急诊就诊增加 2.08%(95%CI:0.88%-3.29%)和消化系统急诊就诊增加 2.14%(95%CI:0.71%-3.59%)相关。3 天和 6 天移动平均 DTR(滞后 02 和滞后 05)每升高 1°C,与心血管系统急诊就诊增加 0.76%(95%CI:0.07%-1.46%)和泌尿系统急诊就诊增加 1.81%(95%CI:0.21%-3.45%)相关。75 岁及以上人群与 DTR 的相关性强于 65-74 岁年龄组。观察到 DTR 的季节修饰效应,且在四个病因中各不相同。

结论

本研究进一步证实了 DTR 是老年人群急诊就诊的一个独立危险因素。针对即将发生的较大温度变化的老年人群和其他高危亚组制定一些预防计划,可能会降低 DTR 对人群健康的影响。

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