Surgical Clinic, Department of Experimental and Clinical Sciences, University of Brescia, Brescia, Italy.
Langenbecks Arch Surg. 2013 Jun;398(5):735-43. doi: 10.1007/s00423-013-1082-5. Epub 2013 Apr 30.
This study aims to recognize factors affecting operative and postoperative outcomes in patients undergoing unilateral laparoscopic adrenalectomy performed by using the transabdominal approach.
From a prospectively collected adrenal database, we performed a retrospective analysis of all patients undergoing unilateral adrenalectomy from July 2002 to December 2011. The outcome measures considered were the following: conversion rate, intra- and postoperative complications, duration of surgery, length of hospital stay, and return-to-work time. Demographic data, American Society of Anesthesiologists score, characteristics of adrenal tumor, and operative and postoperative variables were analyzed to assess their influence on the outcome variables.
A total of 163 laparoscopic adrenalectomies were included. Intraoperative complications, conversion to laparotomy, and postoperative complications were observed in 6.7, 6.1, and 1.8 % of cases, respectively. Conversion to open surgery, intraoperative complications, metastasis, and pheochromocytoma were found to be predictive factors for operative time of >140 min. An operative duration of >140 min was associated with intraoperative complications. Tumor size, intraoperative complications, and adrenalectomy for metastasis significantly increased conversion rate. Hospital stay was extended by operative time of >140 min, conversion to laparotomy, and postoperative complications.
Our study highlights that simple clinical variables, long procedures, and operative complications have a negative impact on procedural outcomes. Based on this, it may be possible to predict cases requiring collaboration with experienced surgeons in order to minimize perioperative morbidity.
本研究旨在识别接受经腹腔入路单侧腹腔镜肾上腺切除术患者的手术和术后结果的影响因素。
我们对 2002 年 7 月至 2011 年 12 月期间所有接受单侧肾上腺切除术的患者进行了前瞻性收集的肾上腺数据库的回顾性分析。考虑的结果衡量标准如下:转化率、术中及术后并发症、手术持续时间、住院时间和恢复工作时间。分析了人口统计学数据、美国麻醉医师协会评分、肾上腺肿瘤特征以及手术和术后变量,以评估它们对结果变量的影响。
共纳入 163 例腹腔镜肾上腺切除术。术中并发症、中转开腹和术后并发症的发生率分别为 6.7%、6.1%和 1.8%。中转开腹、术中并发症、转移和嗜铬细胞瘤被认为是手术时间>140 分钟的预测因素。手术时间>140 分钟与术中并发症相关。肿瘤大小、术中并发症和转移性肾上腺切除术显著增加了转化率。手术时间>140 分钟、中转开腹和术后并发症延长了住院时间。
我们的研究强调,简单的临床变量、手术时间长和手术并发症对手术结果有负面影响。基于此,有可能预测需要与经验丰富的外科医生合作的病例,以最大程度地降低围手术期发病率。