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Excretion of the uraemic metabolite 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid in human urine.

作者信息

McTigue J J, Henderson S J, Lindup W E

机构信息

Department of Pharmacology and Therapeutics, University of Liverpool, UK.

出版信息

Nephron. 1990;55(2):214-5. doi: 10.1159/000185955.

DOI:10.1159/000185955
PMID:2362637
Abstract
摘要

相似文献

1
Excretion of the uraemic metabolite 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid in human urine.尿毒症代谢产物3-羧基-4-甲基-5-丙基-2-呋喃丙酸在人尿中的排泄。
Nephron. 1990;55(2):214-5. doi: 10.1159/000185955.
2
Highly sensitive simultaneous quantification of indoxyl sulfate and 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid in human plasma using ultra-high-performance liquid chromatography coupled with tandem mass spectrometry.采用超高效液相色谱-串联质谱法同时测定人血浆中硫酸吲哚酚和 3-羧基-4-甲基-5-丙基-2-呋喃丙酸的含量
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3
Hypothesis: is accumulation of a furan dicarboxylic acid (3-carboxy-4- methyl-5-propyl-2-furanpropanoic acid) related to the neurological abnormalities in patients with renal failure?
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Reduced renal clearance of furancarboxylic acid, a major albumin-bound organic acid, in undialyzed uremic patients.未透析的尿毒症患者中，主要与白蛋白结合的有机酸呋喃羧酸的肾脏清除率降低。
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Determination of 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid, a major endogenous ligand substance in uremic serum, by high-performance liquid chromatography with ultraviolet detection.采用高效液相色谱-紫外检测法测定尿毒症血清中主要内源性配体物质3-羧基-4-甲基-5-丙基-2-呋喃丙酸。
J Chromatogr. 1987 Mar 20;415(1):110-7. doi: 10.1016/s0378-4347(00)83197-7.
6
Hippuric acid and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid in serum and urine. Analytical approaches and clinical relevance in kidney diseases.血清和尿液中的马尿酸及3-羧基-4-甲基-5-丙基-2-呋喃丙酸。肾脏疾病中的分析方法及临床意义
J Chromatogr. 1990 Feb 2;500:615-27. doi: 10.1016/s0021-9673(00)96096-5.
7
Interaction of 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid, an inhibitor of plasma protein binding in uraemia, with human albumin.
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8
Synthesis and physicochemical properties of the furan dicarboxylic acid, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid, an inhibitor of plasma protein binding in uraemia.
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9
Isolation and characterization of an endogenous drug-binding inhibitor present in uremic serum.尿毒症血清中内源性药物结合抑制剂的分离与鉴定
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Accumulation of furancarboxylic acids in uremic serum as inhibitors of drug binding.呋喃羧酸在尿毒症血清中的蓄积作为药物结合的抑制剂。
Clin Chim Acta. 1988 Apr 15;173(2):127-38. doi: 10.1016/0009-8981(88)90250-1.

引用本文的文献

1
Interaction between two dicarboxylate endogenous substances, bilirubin and an uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid, on human serum albumin.两种二羧酸内源性物质，胆红素和一种尿毒症毒素3-羧基-4-甲基-5-丙基-2-呋喃丙酸，对人血清白蛋白的相互作用。
Pharm Res. 1999 Jun;16(6):916-23. doi: 10.1023/a:1018842506896.
2
Methods of determining plasma and tissue binding of drugs. Pharmacokinetic consequences.药物血浆和组织结合的测定方法。药代动力学后果。
Clin Pharmacokinet. 1992 Dec;23(6):449-68. doi: 10.2165/00003088-199223060-00005.