Kurashige Yuta, Minemuta Tokuya, Nagatani Tetsuo
Department of Dermatology, Hachioji Medical Center, Tokyo Medical University, Tokyo, Japan.
Case Rep Dermatol. 2013 Mar 14;5(1):73-8. doi: 10.1159/000350286. Print 2013 Jan.
The relatively new term dermatoporosis refers to chronic deficiencies in the skin's functions in the elderly population due to aging. This syndrome is marked by chronic cutaneous fragility clinically represented by skin atrophy, senile purpura, stellate pseudoscars, skin laceration, and dissecting hematoma of the skin. In this paper, we report three cases of sacral pressure ulcers presenting primary dermatoporosis on the forearms. Case 1 was a 74-year-old male who presented with a stage IV sacral pressure ulcer. The signs of dermatoporosis appeared on the forearms. Histopathology of the lesions revealed epidermal thinning with loss of rete ridges. Azan and Elastica van Gieson staining demonstrated the degeneration of the dermal collagen fibers and elastic fibers, respectively. In spite of 6 months of treatment, the ulcer failed to heal sufficiently. Case 2 was a 74-year-old male and Case 3 was a 97-year-old female. Both cases presented with a stage II sacral pressure ulcer and dermatoporosis on the forearms. Histopathological examinations and the clinical course of the wound could not be ascertained in Cases 2 and 3. None of the patients had previously used corticosteroids. The presence of a primary dermatoporosis on the forearms in these cases may be associated with the increased risk of pressure ulcer development.
相对较新的术语“皮肤疏松症”指的是老年人群中由于衰老导致的皮肤功能慢性缺陷。这种综合征的特征是慢性皮肤脆弱，临床表现为皮肤萎缩、老年性紫癜、星状假性瘢痕、皮肤撕裂伤和皮肤夹层血肿。在本文中，我们报告了3例骶骨压疮患者，其前臂出现原发性皮肤疏松症。病例1是一名74岁男性，患有IV期骶骨压疮。前臂出现了皮肤疏松症的体征。病变的组织病理学显示表皮变薄， rete嵴消失。阿赞染色和弹性纤维染色分别显示真皮胶原纤维和弹性纤维的变性。尽管经过6个月的治疗，溃疡仍未充分愈合。病例2是一名74岁男性，病例3是一名97岁女性。这两个病例均患有II期骶骨压疮，前臂出现皮肤疏松症。病例2和病例3无法确定组织病理学检查结果和伤口的临床病程。所有患者此前均未使用过皮质类固醇。这些病例中前臂原发性皮肤疏松症的存在可能与压疮发生风险增加有关。
