Dermatology Department, Hospital Central "Dr. Ignacio Morones Prieto"/Faculty of Medicine, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
Gac Med Mex. 2023;159(1):49-54. doi: 10.24875/GMM.M22000737.
Dermatoporosis is a chronic cutaneous fragility syndrome, characterized by skin atrophy, purpura and pseudo-cicatrices.
To determine factors associated with dermatoporosis in a sample of subjects aged ≥ 60 years.
Observational, cross-sectional, descriptive, analytical study of subjects aged ≥ 60 years who underwent history taking, physical examination and application of a self-administered dermatoporosis diagnostic questionnaire. To determine the associated factors, a multivariate logistic regression analysis was used.
In 315 evaluated subjects, the prevalence of dermatoporosis was 29%; 70% were females. Associated risk factors were age > 75 years (p = 0.001), prolonged sun exposure (p = 0.002), use of anticoagulants/antiplatelet medications (p = 0.004), oral steroids (p = 0.03) and chronic kidney disease (p = 0.03), as well as maternal age > 40 years at last pregnancy (p = 0.02), breastfeeding for > 7 months per pregnancy and > 18 cumulative months (p = 0.01). Age < 20 years at first pregnancy and menopause after 45 years were related to dermatoporosis absence. The correlation between self-assessment and clinical diagnosis was considerably high (0.95, p < 0.001).
The risk factors associated with dermatoporosis were similar to those previously reported.
皮肤疏松症是一种慢性皮肤脆弱综合征，其特征为皮肤萎缩、紫癜和假性瘢痕。
在≥60 岁的受试者样本中确定与皮肤疏松症相关的因素。
对≥60 岁的受试者进行观察性、横断面、描述性、分析性研究，进行病史采集、体格检查和应用自我管理的皮肤疏松症诊断问卷。为了确定相关因素，使用了多变量逻辑回归分析。
在 315 名接受评估的受试者中，皮肤疏松症的患病率为 29%；70%为女性。相关的危险因素是年龄>75 岁（p=0.001）、长时间暴露于阳光下（p=0.002）、使用抗凝剂/抗血小板药物（p=0.004）、口服类固醇（p=0.03）和慢性肾病（p=0.03），以及母亲在最后一次妊娠时年龄>40 岁（p=0.02）、每次妊娠母乳喂养>7 个月且累积>18 个月（p=0.01）。首次妊娠年龄<20 岁和绝经年龄>45 岁与皮肤疏松症无关。自我评估与临床诊断之间的相关性非常高（0.95，p<0.001）。
与皮肤疏松症相关的危险因素与先前报道的相似。
