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对于患有单纯疱疹病毒性脑炎的免疫抑制患者，类固醇是否为有益的辅助治疗方法？

Are steroids a beneficial adjunctive therapy in the immunosuppressed patient with herpes simplex virus encephalitis?

作者信息

Lizarraga Karlo J, Alexandre Lucien C, Ramos-Estebanez Ciro, Merenda Amedeo

机构信息

Neurocritical Care Division, Department of Neurology, Miller School of Medicine, University of Miami, Miami, Fla., USA.

出版信息

Case Rep Neurol. 2013 Mar 21;5(1):52-5. doi: 10.1159/000350572. Print 2013 Jan.

DOI:10.1159/000350572
PMID:23626565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3635685/
Abstract

Few reports describe the reactivation of latent herpes simplex virus causing encephalitis (HSVE) in patients undergoing brain radiation therapy and a concomitant steroid regimen. The role for steroid use in the treatment of patients with HSVE has not been fully elucidated. We report the case of a female patient immunosuppressed by steroids and brain radiation who developed HSVE and responded to acyclovir and dexamethasone.

摘要

鲜有报告描述在接受脑部放射治疗并同时使用类固醇疗法的患者中，潜伏的单纯疱疹病毒引发脑炎（HSVE）再激活的情况。类固醇在HSVE患者治疗中的作用尚未完全阐明。我们报告了一例女性患者，该患者因类固醇和脑部放射治疗而免疫抑制，发生了HSVE，并对阿昔洛韦和地塞米松有反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1c/3635685/f1ce59b811db/crn-0005-0052-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1c/3635685/224ac5adc1e5/crn-0005-0052-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1c/3635685/f1ce59b811db/crn-0005-0052-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1c/3635685/224ac5adc1e5/crn-0005-0052-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d1c/3635685/f1ce59b811db/crn-0005-0052-g02.jpg

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