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一项针对入院老年人营养状况与生活质量之间关联的调查。

An investigation into the association between nutritional status and quality of life in older people admitted to hospital.

作者信息

Rasheed S, Woods R T

机构信息

Department of Nutrition & Dietetics, Betsi Cadwaladr University Health Board, Bangor, UK.

出版信息

J Hum Nutr Diet. 2014 Apr;27(2):142-51. doi: 10.1111/jhn.12072. Epub 2013 Apr 30.

Abstract

BACKGROUND

Malnutrition is prevalent in acute hospitals and malnourished patients have an increased risk of morbidity and mortality. Studies of malnutrition and quality of life (QoL) are generally limited by both the nutritional and QoL assessment methods employed. The present study aimed to evaluate the relationship between malnutrition, as assessed using a range of nutritional assessment methods, and QoL, as measured by EuroQol-5D-3L and Short-Form (SF)-36 questionnaires.

METHODS

The study comprised a prospective cross-sectional study of malnutrition and QoL in 149 inpatients aged 65-99 years. Exclusion criteria were: terminal illness, active malignancy, lack of capacity to consent and severe communication difficulties. Spearman's rank correlation coefficient was used to test the association between QoL indices and nutritional markers. QoL scores for those scoring above and below thresholds for nutritional risk were compared. Regression models were created to identify nutritional indices contributing to the variability of QoL.

RESULTS

There were significant associations between QoL scores and the Mini Nutritional Assessment (MNA)-SF. Clear differences were evident between malnourished and well-nourished patients (on the MNA-SF), those with low and normal arm muscle circumference and those with good and poor physical function. Regression analysis showed that nutritional scores and functional status made independent contributions to the prediction of QoL. The effect on food intake, mobility and psychological stress/acute disease also had a significant influence.

CONCLUSIONS

Malnutrition risk is linked to a poorer QoL in older people on admission to hospital. Functional status and eating-related factors are major influencers on QoL in this group. These findings reinforce the role of nutrition as a priority with respect to achieving improvements in QoL.

摘要

背景

营养不良在急症医院中普遍存在,营养不良患者的发病和死亡风险增加。营养不良与生活质量(QoL)的研究通常受到所采用的营养评估方法和生活质量评估方法的限制。本研究旨在评估使用一系列营养评估方法评估的营养不良与通过欧洲五维健康量表(EuroQol-5D-3L)和简明健康状况调查问卷(Short-Form,SF-36)测量的生活质量之间的关系。

方法

该研究包括一项对149名65至99岁住院患者的营养不良和生活质量的前瞻性横断面研究。排除标准为:晚期疾病、活动性恶性肿瘤、缺乏同意能力和严重沟通困难。采用Spearman等级相关系数检验生活质量指数与营养指标之间的关联。比较了营养风险得分高于和低于阈值者的生活质量得分。建立回归模型以确定导致生活质量变异的营养指标。

结果

生活质量得分与微型营养评定法(MNA)简表之间存在显著关联。在营养不良和营养良好(根据MNA简表)的患者之间、手臂肌肉周长低和正常者之间以及身体功能良好和较差者之间存在明显差异。回归分析表明,营养得分和功能状态对生活质量的预测具有独立贡献。对食物摄入、活动能力和心理压力/急性疾病的影响也有显著影响。

结论

入院时,营养不良风险与老年人较差的生活质量相关。功能状态和饮食相关因素是该组生活质量的主要影响因素。这些发现强化了营养在改善生活质量方面作为优先事项的作用。

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