Leeds Institute of Health Sciences, University of Leeds, UK; Department of Clinical and Health Psychology, Leeds Teaching Hospitals NHS Trust, UK.
J Cyst Fibros. 2013 Dec;12(6):794-6. doi: 10.1016/j.jcf.2013.04.002. Epub 2013 Apr 26.
The International Depression and Anxiety Epidemiological Study (TIDES) in CF attempts to provide prevalence data for mental distress in CF patients. The current study reports the results from the UK pilot in a single major CF centre in which the performances of different instruments were compared, and risk of self harm measured.
Two mental health assessment screening instruments, the Hospital Anxiety and Depression Scale (HADS) and the Patient Health Questionnaire for depression (PHQ-9) were given to all adults with CF attending the Regional Adult CF Unit in Leeds, UK.
232 patients took part. 13 (5.6%) scored in the clinical range for depression on the HADS and 78 (33.4%) on the PHQ9. The suicide risk item on the PHQ9 was endorsed by 24 patients (10.4%).
Major discrepancies were found in rates of depression detected by two popular screening tools. A significant minority of respondents indicated suicidal ideation. Work is needed to identify the most appropriate screening tool for depression in this population, and it is important that this includes an assessment of self harm.
国际抑郁和焦虑流行病学研究（TIDES）在 CF 中试图提供 CF 患者精神困扰的患病率数据。本研究报告了英国在莱斯特大学单一主要 CF 中心的试点研究结果，其中比较了不同工具的性能，并测量了自我伤害的风险。
对所有在英国利兹地区成人 CF 单位就诊的成年 CF 患者使用两种心理健康评估筛查工具，即医院焦虑和抑郁量表（HADS）和患者健康问卷抑郁量表（PHQ-9）。
共有 232 名患者参与。13 名（5.6%）患者在 HADS 上的抑郁临床评分中得分，78 名（33.4%）在 PHQ9 上得分。PHQ9 上的自杀风险项目得到了 24 名患者（10.4%）的认可。
两种流行的筛查工具检测到的抑郁率存在显著差异。相当一部分受访者表示有自杀意念。需要努力确定该人群中最适合的抑郁筛查工具，重要的是，这包括对自我伤害的评估。
