Ellis C J, Dewhurst A G, Cooper M, Brenton D P, Dathan J R
Department of Medicine, Royal South Hants Hospital, Southampton, UK.
Postgrad Med J. 1990 Mar;66(773):235-7. doi: 10.1136/pgmj.66.773.235.
A 52 year old man presented with myoglobinuria-induced acute renal failure requiring dialysis. Despite renal biopsy, the cause of the myoglobinuria was not established until he re-presented a year later with a milder episode. At this stage investigations, including a muscle biopsy, demonstrated a defect in fatty acid oxidation amenable to dietary and lifestyle advice. This report emphasizes the importance of reaching a definitive diagnosis in myoglobinuria.
一名52岁男性因肌红蛋白尿诱发急性肾衰竭,需要进行透析治疗。尽管进行了肾活检,但直到一年后他再次出现较轻微发作时,肌红蛋白尿的病因才得以明确。在这个阶段,包括肌肉活检在内的各项检查显示,脂肪酸氧化存在缺陷,可通过饮食和生活方式建议加以改善。本报告强调了明确诊断肌红蛋白尿的重要性。