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同期双侧全膝关节置换术:150例患者的前瞻性研究

Simultaneous bilateral total knee replacement: a prospective study of 150 patients.

作者信息

Jain Sanjeev, Wasnik Sandeep, Mittal Amber, Sohoni Sameep, Kasture Sarang

机构信息

Dr LH Hiranandani Hospital, Mumbai, India.

出版信息

J Orthop Surg (Hong Kong). 2013 Apr;21(1):19-22. doi: 10.1177/230949901302100107.

Abstract

PURPOSE

To evaluate the safety of simultaneous bilateral total knee replacement (TKR).

METHODS

124 women and 26 men (mean age, 66 years) underwent simultaneous bilateral TKR for tricompartmental osteoarthritis using a posteriorstabilised, high-flexion implant. All patients underwent dobutamine stress echocardiography for detection of any silent cardiac comorbidity by a cardiologist. None had any adverse effect after testing. Five patients had positive outcome and underwent coronary angiography to detect any significant coronary blockage. Functional outcome was evaluated using the Knee Society Score (KSS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC). Tranexamic acid was given intravenously to reduce peri-operative blood loss. Femoral blocks and patient-controlled analgesia were used to facilitate early recovery. Aggressive physiotherapy was allowed. Patients were followed up at months 3, 6, and 12, and yearly thereafter.

RESULTS

At the 2-year follow-up, the mean range of motion improved from 95º to 129º (p=0.032), the mean KSS from 120 to 158 (p<0.001), and the WOMAC from 51 to 88 (p=0.002). One patient developed patellar crepitus at week 6, which resolved with conservative treatment. Another patient developed infection in both knees at month 6. Despite salvage procedures, infection recurred after 3 months and the patient underwent bilateral arthrodesis. No patient developed deep vein thrombosis or pulmonary embolism, myocardial infarction, atrial fibrillation, or other cardiac event.

CONCLUSION

Simultaneous bilateral TKR is safe for properly selected patients.

摘要

目的

评估同期双侧全膝关节置换术(TKR)的安全性。

方法

124名女性和26名男性(平均年龄66岁)因三关节间骨关节炎接受了同期双侧TKR,使用后稳定型高屈曲植入物。所有患者均接受了多巴酚丁胺负荷超声心动图检查,由心脏病专家检测是否存在任何无症状的心脏合并症。检查后均未出现任何不良反应。5名患者检查结果呈阳性,接受了冠状动脉造影以检测是否存在任何严重冠状动脉阻塞。使用膝关节协会评分(KSS)和西安大略和麦克马斯特大学关节炎指数(WOMAC)评估功能结果。静脉注射氨甲环酸以减少围手术期失血。使用股神经阻滞和患者自控镇痛以促进早期恢复。允许积极进行物理治疗。在术后3个月、6个月和12个月进行随访,此后每年随访一次。

结果

在2年随访时,平均活动范围从95°改善至129°(p = 0.032),平均KSS从120提高至158(p < 0.001),WOMAC从51提高至88(p = 0.002)。1例患者在术后第6周出现髌股关节摩擦音,经保守治疗后缓解。另1例患者在术后第6个月双膝发生感染。尽管采取了挽救措施,但3个月后感染复发,该患者接受了双侧关节融合术。没有患者发生深静脉血栓形成或肺栓塞、心肌梗死、心房颤动或其他心脏事件。

结论

对于经过适当选择的患者,同期双侧TKR是安全的。

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