Klausmann Gerhard, Hramiak Irene, Qvist Marianne, Mikkelsen Kristian Handberg, Guo Xiaohui
Internal Medicine Diabetology Practice, Aschaffenburg, Germany.
Patient Prefer Adherence. 2013 Apr 5;7:285-92. doi: 10.2147/PPA.S41929. Print 2013.
Improving adherence to insulin treatment for better glycemic control remains a challenge in the management of diabetes. New technological aids are required to help support adherence. This study evaluated preference for the NovoPen(®) 5 (NP5), a durable insulin pen with memory function, compared with the HumaPen Luxura(®) (HPL) among patients with diabetes and health care professionals.
This crossover, multicenter usability study included insulin pen-experienced patients with diabetes and health care professionals treating patients with diabetes in Canada, China, and Germany. Participants evaluated NP5 and HPL in a randomized order by performing handling tasks in a usability test related to everyday use during a face-to-face interview. Tasks, pens, and preferences were assessed by completing a questionnaire comprised of rating and open-ended questions relating to confidence in everyday diabetes management.
Overall, 300 patients with diabetes and 150 health care professionals participated in the study. Significantly more participants preferred NP5 (81%) to HPL (18%) (P < 0.001). Also, 82% of patients with diabetes had more confidence in NP5 for managing their daily injections versus 11% with HPL (P < 0.001), and 7% had no preference. Memory function was most helpful in giving patients with diabetes confidence about when they last injected (63%), how much insulin they last injected (62%) and improving diabetes management (55%). Participants gave higher ratings to NP5 than to HPL on all parameters relating to performing an injection (ease of handling, satisfaction when using the pen, convenience of using the pen day-to-day, quality of the pen, and the extent to which the pen meets their needs; P < 0.05 for all comparisons).
NP5 was preferred to HPL by most participants. Significantly more patients with diabetes had more confidence for managing daily insulin injections when using NP5, the pen with a memory function.
在糖尿病管理中，提高胰岛素治疗依从性以实现更好的血糖控制仍是一项挑战。需要新的技术辅助手段来支持依从性。本研究评估了糖尿病患者和医疗保健专业人员对诺和笔5（NP5）（一种具有记忆功能的耐用胰岛素笔）与优伴笔（HPL）的偏好。
这项交叉、多中心可用性研究纳入了加拿大、中国和德国有胰岛素笔使用经验的糖尿病患者以及治疗糖尿病患者的医疗保健专业人员。参与者通过在面对面访谈中进行与日常使用相关的可用性测试中的操作任务，以随机顺序评估NP5和HPL。通过完成一份由与日常糖尿病管理信心相关的评分和开放式问题组成的问卷来评估任务、笔和偏好。
总体而言，300名糖尿病患者和150名医疗保健专业人员参与了研究。明显更多的参与者更喜欢NP5（81%）而非HPL（18%）（P < 0.001）。此外，82%的糖尿病患者对NP5管理每日注射更有信心，而对HPL有信心的为11%（P < 0.001），7%没有偏好。记忆功能在让糖尿病患者对上次注射时间（63%）、上次注射的胰岛素量（62%）以及改善糖尿病管理（55%）方面最有帮助。在与注射相关的所有参数（操作便利性、使用笔时的满意度、日常使用笔的便利性、笔的质量以及笔满足其需求的程度）上，参与者对NP5的评分高于HPL（所有比较P < 0.05）。
大多数参与者更喜欢NP5而非HPL。明显更多的糖尿病患者在使用具有记忆功能的NP5笔进行每日胰岛素注射管理时更有信心。
