Hall Rebecca L, Willgoss Thomas, Humphrey Louise J, Kongsø Jens Harald
Adelphi Values, Adelphi Mill, Bollington, Cheshire, UK.
Novo Nordisk A/S, Novo Allé, Bagsværd, Denmark.
Patient Prefer Adherence. 2014 May 23;8:775-88. doi: 10.2147/PPA.S61248. eCollection 2014.
Adherence to treatment is an important issue in chronic disease management and an indicator of patients' ability to self-manage their condition and treatment. Some drug-dispensing and drug-delivery devices have been designed to support patients' medication-taking behavior by including dose-memory and combined dose-memory and dose-reminder functions, which electronically store, and visually display dose-history information, enabling the patient to review, monitor, and/or be actively reminded about their medication doses.
This literature review explored the role and impact of these devices on patients' treatment adherence, confidence with, and self-management of their condition and treatment.
A search of MEDLINE, Embase, and PsycINFO was performed to identify articles published in English from 2003-2013 that studied the effect of devices with dose-memory and combined dose-memory and dose-reminder functions on treatment adherence and users' (patients, health care professionals [HCPs], and caregivers) confidence, self-management behavior, and attitudes.
The database searches yielded 940 abstracts from which 13 articles met the inclusion criteria and were retained. Devices with dose-memory and combined dose-memory and dose-reminder functions were found to improve self-reported and electronically monitored treatment adherence in chronic conditions such as asthma, diabetes, and HIV. The ability of the devices to provide dose-history information and active medication reminders was considered valuable in disease management by patients, caregivers, and HCPs. The devices were found to enhance patients' confidence in, and motivation to manage their medication and condition, and help reduce forgotten or incorrect medication dosing.
The incorporation of dose-memory and combined dose-memory and dose-reminder functions in drug-delivery devices can improve patients' adherence, confidence, and self-management behavior. They can target non-intentional barriers to adherence and can provide a means of improving disease control and clinical outcomes, thereby offering clinical and economic value. This review highlights the importance of conducting further qualitative and quantitative research to further understand the value and impact of these types of devices on patients' long-term adherence to, and self-management of treatment.
坚持治疗是慢性病管理中的一个重要问题，也是患者自我管理病情和治疗能力的一个指标。一些药物分发和给药设备被设计用于支持患者的服药行为，具有剂量记忆以及剂量记忆与剂量提醒相结合的功能，能够以电子方式存储并直观显示剂量历史信息，使患者能够回顾、监测和/或被积极提醒其服药剂量。
本综述探讨了这些设备在患者治疗依从性、对病情和治疗的信心以及自我管理方面的作用和影响。
检索了MEDLINE、Embase和PsycINFO数据库，以识别2003年至2013年期间发表的英文文章，这些文章研究了具有剂量记忆以及剂量记忆与剂量提醒相结合功能的设备对治疗依从性以及使用者（患者、医护人员和护理人员）的信心、自我管理行为和态度的影响。
数据库检索得到940篇摘要，其中13篇文章符合纳入标准并被保留。具有剂量记忆以及剂量记忆与剂量提醒相结合功能的设备被发现可提高在哮喘、糖尿病和艾滋病毒等慢性病中自我报告的以及电子监测的治疗依从性。这些设备提供剂量历史信息和主动服药提醒的能力在患者、护理人员和医护人员的疾病管理中被认为具有价值。这些设备被发现可增强患者对管理药物和病情的信心及积极性，并有助于减少漏服或错服药物的情况。
在给药设备中纳入剂量记忆以及剂量记忆与剂量提醒相结合的功能可提高患者的依从性、信心和自我管理行为。它们可以针对依从性的非故意障碍，并可提供一种改善疾病控制和临床结果的方法，从而具有临床和经济价值。本综述强调了进行进一步定性和定量研究以进一步了解这类设备对患者长期治疗依从性和自我管理的价值和影响的重要性。
