Mishunina T M
Vopr Med Khim. 1990 Mar-Apr;36(2):22-4.
Content of gamma-aminobutyric acid in blood plasma of healthy persons did not depend on sex and age and of women--on the phase of menstrual cycle. Activity of glutamate decarboxylase was higher 1.5-fold in blood plasma of women as compared with that of men values; a decrease in the enzymatic activity was observed in men after 30 years old and in women--after 40 years old. Activity of glutamate decarboxylase was higher in blood plasma of young and middle age women during the lutein phase of menstrual cycle as compared with the follicular phase, while this ratio reversed its direction in blood plasma of older women as a result of distinct decrease in the enzymatic activity during the lutein phase of the cycle.
健康人血浆中γ-氨基丁酸的含量不取决于性别和年龄，女性血浆中γ-氨基丁酸的含量也不取决于月经周期阶段。女性血浆中谷氨酸脱羧酶的活性比男性高1.5倍；30岁以后男性的酶活性下降，40岁以后女性的酶活性下降。与卵泡期相比，中青年女性在月经周期黄体期血浆中谷氨酸脱羧酶的活性较高，而老年女性血浆中由于黄体期酶活性明显下降，这一比例则相反。
