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[经口致敏后对己烯醛具有不同抵抗力的豚鼠肝脏血红素蛋白的周转情况]

[Turnover of liver hemoproteins in guinea pigs with various resistance to hexenal after peroral sensitization].

作者信息

Mal'tsev G Iu, Krzhechkovskaia V V, Marokko I N, Gapparov M M

出版信息

Vopr Med Khim. 1990 Mar-Apr;36(2):68-71.

PMID:2363264
Abstract

Patterns of hemoproteins turnover were studied in microsomal and mitochondrial fractions of liver tissue of guinea pigs with various duration of hexenal sleep; these patterns were calculated by means of modified procedure involving incorporation of 14C-aminolevulinic acid. Increase in turnover of microsomal cytochromes corresponded to decrease of their content in animals with short-term sleep simultaneously with a decrease in the lethal index after sensitization by means of ovalbumin.

摘要

研究了不同时长己烯醛睡眠状态下豚鼠肝组织微粒体和线粒体部分血红素蛋白的周转模式;这些模式是通过改进的方法计算得出的,该方法涉及掺入14C-氨基乙酰丙酸。微粒体细胞色素周转的增加与短期睡眠动物中其含量的减少相对应,同时通过卵清蛋白致敏后致死指数降低。

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