Orlova S V, Godneva A T, Ignat'ev G M, Bystrova S I
Vopr Virusol. 1990 Jan-Feb;35(1):59-61.
The parameters of humoral and cell-mediated immunity after inoculation of the infectious and inactivated antigen of Lassa virus to rabbits which are insusceptible to this infection were studied. Lassa virus antigen was demonstrated to induce synthesis of specific antibodies in rabbits the level of which was proportional to the dose of inoculation and the time of immunization. The results of leukocyte blastogenesis test and delayed type hypersensitivity test confirm the development of sensitization to inactivated Lassa virus in immune rabbits.
对接种对拉沙病毒感染不敏感的家兔注射拉沙病毒感染性抗原和灭活抗原后体液免疫和细胞介导免疫的参数进行了研究。结果表明，拉沙病毒抗原可诱导家兔产生特异性抗体，其水平与接种剂量和免疫时间成正比。白细胞增殖试验和迟发型超敏反应试验结果证实，免疫家兔对灭活拉沙病毒产生了致敏反应。
