Tomori O
Bull World Health Organ. 1980;58(2):293-6.
Inactivated Lassa virus complement-fixing antigen is normally prepared as a wet frozen antigen, and shipped in dry ice from the Center for Disease Control, Atlanta, Georgia, USA, to other laboratories not equipped for handling live Lassa virus. However, with this antigen there is a considerable loss of potency during shipping. In the search for a more stable antigen, inactivated Lassa antigen was lyophilized and subjected to different storage temperatures. Lyophilization did not significantly affect the CF titre, and the lyophilized antigen remained stable for 15 and 28 days at 25 degrees C and 4 degrees C, respectively.
灭活拉沙病毒补体结合抗原通常制成湿冻抗原，从美国佐治亚州亚特兰大疾病控制中心用干冰运往其他没有处理活拉沙病毒条件的实验室。然而，这种抗原在运输过程中效价会有相当大的损失。为寻找更稳定的抗原，将灭活拉沙抗原冻干并置于不同储存温度下。冻干对补体结合滴度没有显著影响，冻干抗原在25摄氏度和4摄氏度下分别可稳定保存15天和28天。
