1st Cardiology Clinic, The Regional United Hospital, Kielce, Poland.
Kardiol Pol. 2013;71(11):1140-6. doi: 10.5603/KP.a2013.0087. Epub 2013 Apr 30.
To assess blood pressure (BP) load in a population of treated hypertensive patients.
The study group consisted of 137 hypertensive adults, including 75 (54.75%) men and 62 (45.25%) women, with either formerly or newly diagnosed hypertension based on office BP measurements. The median age in the whole study group was 52 years (47 and 56 years among men and women, respectively). The mean body mass index (BMI) was 27 ± 4 kg/m², and median duration of hypertension was 3 years. We divided the study group into subgroups depending on age, gender, BMI, and duration of hypertension. All patients underwent single 24-h ambulatory BP monitoring. We calculated 24-h, daytime and nighttime BP loads separately for systolic and diastolic BP. Statistical analysis was carried out using the SPSS 15.0 environment.
Men were significantly younger than women (48.17 vs. 55.48 years, p < 0.02). Mean BMI was higher in men than women (28 vs. 26 kg/m², p < 0.044). There were no differences in the mean values of BP load depending on gender, BMI and, duration of hypertension (p = NS). Twenty-four hour and daytime diastolic BP load was higher in patients aged 41-65 years than in patients above 65 years (32.4 vs. 20.8%, p < 0.04; and 29.6 vs. 17.5%, p < 0.03). A negative correlation was found between daytime diastolic BP load and age (r = -0.19, p < 0.026) and a positive correlation was found between night time systolic BP load and age (r = 0.24, p < 0.005).
There was no relationship between BP load and gender, BMI, and duration of hypertension. Diastolic BP load was age-related. Middle-aged patients were characterised by significantly higher values of 24-h and daytime diastolic BP load than the elderly patients.
评估治疗高血压患者的血压负荷。
研究组包括 137 名高血压成年患者，其中 75 名（54.75%）为男性，62 名（45.25%）为女性，根据诊室血压测量值诊断为高血压。整个研究组的中位年龄为 52 岁（男性为 47 岁，女性为 56 岁）。平均体重指数（BMI）为 27 ± 4 kg/m²，高血压中位病程为 3 年。我们根据年龄、性别、BMI 和高血压病程将研究组分为亚组。所有患者均行单次 24 小时动态血压监测。我们分别计算收缩压和舒张压的 24 小时、白天和夜间血压负荷。统计分析采用 SPSS 15.0 环境。
男性明显比女性年轻（48.17 岁比 55.48 岁，p < 0.02）。男性的平均 BMI 高于女性（28 比 26 kg/m²，p < 0.044）。性别、BMI 和高血压病程对血压负荷的平均值没有影响（p = NS）。41-65 岁患者的 24 小时和白天舒张压负荷高于 65 岁以上患者（32.4%比 20.8%，p < 0.04；29.6%比 17.5%，p < 0.03）。日间舒张压负荷与年龄呈负相关（r = -0.19，p < 0.026），夜间收缩压负荷与年龄呈正相关（r = 0.24，p < 0.005）。
血压负荷与性别、BMI 和高血压病程无关。舒张压负荷与年龄有关。中年患者的 24 小时和日间舒张压负荷明显高于老年患者。
