Larson Ross N, Schmiedt Chad W, Wang Andrea, Lawrence Jessica, Howerth Elizabeth W, Holmes Shannon P, Grey Susan W
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA.
J Am Vet Med Assoc. 2013 May 15;242(10):1398-404. doi: 10.2460/javma.242.10.1398.
A 40.3-kg (88.7-lb) 6-year-old spayed female Labrador Retriever was evaluated because of acute unilateral epistaxis.
During the initial evaluation of the dog, systemic hypertension and a left adrenal gland mass were detected. The left adrenal gland mass was surgically removed; results of histologic examination of the mass indicated it was a pheochromocytoma. Ten months later, the dog was evaluated because of persistent systemic hypertension and development of polyuria, polydipsia, and excessive panting. Abdominal ultrasonography revealed a mass in the cranial aspect of the right adrenal gland; results of MRI suggested the mass was a malignant tumor.
Epistaxis resolved after treatment and resolution of severe systemic hypertension. A partial right adrenalectomy was performed to remove the right adrenal gland mass. Results of histologic examination of the mass indicated it was a well-differentiated carcinoma of the cortex of the adrenal gland. Results of ACTH stimulation tests after surgery indicated the dog had adequate adrenal gland function.
Partial adrenalectomy may be a safe and feasible treatment option to preserve adrenal gland function in dogs with small eccentrically located adrenal gland masses, particularly for dogs that have undergone removal of the contralateral adrenal gland.
一只40.3千克(88.7磅)的6岁绝育雌性拉布拉多猎犬因急性单侧鼻出血接受评估。
在对该犬进行初步评估期间,检测到系统性高血压和左肾上腺肿块。左肾上腺肿块通过手术切除;肿块的组织学检查结果表明它是一个嗜铬细胞瘤。十个月后,该犬因持续性系统性高血压以及多尿、多饮和过度喘气的症状而接受评估。腹部超声检查发现右肾上腺颅侧有一个肿块;磁共振成像结果提示该肿块是一个恶性肿瘤。
在治疗并解决严重的系统性高血压后,鼻出血症状消失。进行了部分右肾上腺切除术以切除右肾上腺肿块。肿块的组织学检查结果表明它是肾上腺皮质的高分化癌。术后促肾上腺皮质激素刺激试验结果表明该犬肾上腺功能正常。
对于肾上腺有小的偏心性肿块的犬,尤其是对侧肾上腺已被切除的犬,部分肾上腺切除术可能是一种安全可行的治疗选择,可保留肾上腺功能。